Acetone cyanohydrin
Synonyms: 2-Hydroxy-2-methylpropanenitrile
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical Name
Acetone cyanohydrin
Product Form
Substance
Catalogue No.
AL0066
CAS Number
75-86-5
EC Number
200-909-4
EC Index Number
607-001-00-0
Grade
98.5% For Synthesis
HSN Code
29269000
Molecular Formula
C4H7NO
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name
Acetone cyanohydrin
Catalogue No.
AL0066
Product form
Substance
CAS Number
75-86-5
EC Number
200-909-4
Grade
98.5% For Synthesis
EC Index Number
607-001-00-0
Chemical Formula
C4H7NO
HSN Code
29269000
Synonyms
2-Hydroxy-2-methylpropanenitrile
Chemical Structure
-
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture
Used as a precursor in organic synthesis and as a controlled HCN-releasing reagent.
Uses advised against
Not specified
1.3 Details of the supplier of the safety data sheet
Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute Tox. 2; Acute Tox. 1; Aquatic Acute 1; Aquatic Chronic 1
Classification source
ECHA C&L Inventory via PubChem CID 6406 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 Label elements
Hazard pictograms
Acute Toxic, Environmental Hazard
Signal word
Danger
Hazard statements
H300: Fatal if swallowed; H310: Fatal in contact with skin; H330: Fatal if inhaled; H400: Very toxic to aquatic life; H410: Very toxic to aquatic life with long lasting effects
2.3 Other hazards
Other hazards
Releases hydrogen cyanide upon decomposition; highly toxic.
SECTION 3: Composition/information on ingredients
3.1 Substance
Name
Acetone cyanohydrin
CAS No.
75-86-5
SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation
If this chemical has been inhaled, remove the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the person warm and at rest.
First-aid measures after skin contact
If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.
First-aid measures after eye contact
If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.
First-aid measures after ingestion
If this chemical has been swallowed, get medical attention immediately.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use
Headache, dizziness, nausea, respiratory distress, and potential cyanide poisoning symptoms.
4.3 Indication of any immediate medical attention and special treatment needed
General information
Treat symptomatically. Show this safety data sheet to the treating physician.
SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified
5.2 Special hazards arising from the substance or mixture
Special procedures
The vapour is heavier than air.
5.3 Advice for firefighters
Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.
SECTION 6: Accidental release measures
6.1.1 For non-emergency personnel
Emergency procedures
Evacuate area. Wear appropriate protective equipment. Contain and neutralize spill with sodium bicarbonate or lime.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder.
6.4 Reference to other sections
Reference
Not specified
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling
Use in a fume hood with appropriate PPE. Avoid contact with skin and eyes.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Provision to contain effluent from fire extinguishing. Separated from strong bases, acids, water and food and feedstuffs. Well closed. Keep in a well-ventilated room.
SECTION 8: Exposure controls/personal protection
8.2 Exposure controls
Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use a NIOSH-approved respirator if exposure limits are exceeded.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state
Liquid
Colour
Colorless to pale yellow
Odour
Distinct strong cyanide odor
Odour threshold
Not specified
pH value
Not specified
Relative evaporation rate (butylacetate=1)
Not specified
Melting point
-19 °C
Freezing point
Not specified
Boiling point
95 °C
Flash point
165 °F (74 °C) (closed cup)
Auto-ignition temperature
1270 °F (688 °C)
Decomposition temperature
Decomposes at elevated temperatures, releasing HCN
Flammability (solid, gas)
Not applicable
Vapour pressure
Vapor pressure = 0.8 mm Hg at 20 °C
Relative vapour density at 20°C
2.96 (Air = 1)
Density
Specific gravity: 0.9267 at 25 °C/4 °C
Solubility
Freely soluble in usual organic solvents; insoluble in petroleum ether and carbon disulfide.
Log Pow
Not specified
Viscosity, kinematic
Not specified
Viscosity, dynamic
Not specified
Explosive properties
Not explosive under normal conditions
Oxidising properties
Not oxidizing
Explosive limits
Not specified
SECTION 10: Stability and reactivity
10.1 Reactivity
Reactivity
Stable under normal conditions; reacts with strong acids and bases.
10.2 Chemical stability
Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
Possibility of hazardous reactions
Decomposes rapidly on heating and on contact with bases and water. This produces highly toxic and flammable hydrogen cyanide (see ICSC 0492) and acetone (see ICSC 0087). Reacts violently with acids and oxidants.
10.4 Conditions to avoid
Conditions to avoid
Avoid contact with incompatible materials and excessive heat.
10.5 Incompatible materials
Incompatible materials
Strong oxidizers, strong acids, and bases.
10.6 Hazardous decomposition products
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of hydrogen cyanide.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
LD50 Rat oral 0.17 g/kg; LD50 Rat oral 19,300 ug/kg; LD50 Mouse oral 15 mg/kg.
Skin corrosion/irritation
Not classified (based on available data)
Serious eye damage/irritation
Not classified (based on available data)
Respiratory or skin sensitisation
Not classified (based on available data)
Germ cell mutagenicity
Not classified (based on available data)
Carcinogenicity
Not classified (based on available data)
Specific target organ toxicity (single exposure)
Not classified (based on available data)
Specific target organ toxicity (repeated exposure)
Not classified (based on available data)
SECTION 12: Ecological information
12.1 Toxicity
Toxicity information
Not specified
12.2 Persistence - degradability
Persistence - degradability
Not specified
12.3 Bioaccumulative potential
Bioaccumulative potential
Not specified
12.4 Mobility in soil
Mobility in soil
Not specified
12.6 Other adverse effects
Environmental precautions
Not specified
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.
SECTION 14: Transport information
14.1 UN number
UN-No. (ADR)
UN 1541
UN-No. (IMDG)
UN 1541
UN-No. (IATA)
UN 1541
UN-No. (ADN)
UN 1541
UN-No. (RID)
UN 1541
14.2 UN proper shipping name
Proper Shipping Name (ADR)
Acetone cyanohydrin
Proper Shipping Name (IMDG)
Acetone cyanohydrin
Proper Shipping Name (IATA)
Acetone cyanohydrin
Proper Shipping Name (ADN)
Acetone cyanohydrin
Proper Shipping Name (RID)
Acetone cyanohydrin
14.3 Transport hazard class(es)
Transport hazard class(es)
6.1
14.4 Packing group
Packing group (ADR)
I
Packing group (IMDG)
I
Packing group (IATA)
I
Packing group (ADN)
I
Packing group (RID)
I
14.5 Environmental hazards
Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations
Not specified
SECTION 16: Other Information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.