Capsaicin

Synonyms: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical Name Capsaicin
Product Form Substance
Catalogue No. AL1125
CAS Number 404-86-4
EC Number 206-969-8
EC Index Number 607-123-00-0
Grade 65% Purified
HSN Code 29181190
Molecular Formula C18H27NO3
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name Capsaicin
Catalogue No. AL1125
Product form Substance
CAS Number 404-86-4
EC Number 206-969-8
Grade 65% Purified
EC Index Number 607-123-00-0
Chemical Formula C18H27NO3
HSN Code 29181190
Synonyms N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
Chemical Structure -
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture Research and development in pain management and topical analgesics.
Uses advised against Not specified
1.3 Details of the supplier of the safety data sheet
Company identification Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
Classification source ECHA C&L Inventory via PubChem CID 1548943 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 Label elements
Hazard pictograms Corrosive, Irritant
Signal word Danger
Hazard statements H302: Harmful if swallowed; H315: Causes skin irritation; H318: Causes serious eye damage
2.3 Other hazards
Other hazards May cause skin and eye irritation; harmful if swallowed or inhaled.
SECTION 3: Composition/information on ingredients
3.1 Substance
Name Capsaicin
CAS No. 404-86-4
SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and seek medical attention.
First-aid measures after ingestion Rinse mouth. Do not induce vomiting. Seek medical attention immediately.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use Irritation of the skin, eyes, and respiratory tract; potential for nausea and vomiting if ingested.
4.3 Indication of any immediate medical attention and special treatment needed
General information Treat symptomatically. Show this safety data sheet to the treating physician.
SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Unsuitable extinguishing media Not specified
5.2 Special hazards arising from the substance or mixture
Special procedures Combustible material; may produce toxic fumes when burned.
5.3 Advice for firefighters
Protection during firefighting Do not enter fire area without proper protective equipment, including respiratory protection.
SECTION 6: Accidental release measures
6.1.1 For non-emergency personnel
Emergency procedures Evacuate area and ventilate. Wear appropriate protective equipment. Contain and collect spillage.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up Use appropriate absorbent materials and dispose of in accordance with local regulations.
6.4 Reference to other sections
Reference Not specified
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling Handle with gloves and eye protection. Avoid inhalation and contact with skin.
Hygiene measures Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8 °C.
SECTION 8: Exposure controls/personal protection
8.2 Exposure controls
Hand protection Handle with gloves.
Eye protection Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin and body protection Complete suit protecting against chemicals. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection Use appropriate respiratory protection if ventilation is inadequate.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state Solid
Colour White to pale yellow
Odour Highly volatile with a pungent odor
Odour threshold Not specified
pH value Not applicable
Relative evaporation rate (butylacetate=1) Not specified
Melting point 65 °C
Freezing point Not specified
Boiling point BP: 210-220 °C at 0.01 mm Hg
Flash point 113 °C (235 °F) - closed cup
Auto-ignition temperature Not specified
Decomposition temperature Not specified
Flammability (solid, gas) Combustible
Vapour pressure Not specified
Relative vapour density at 20°C Not specified
Density Not specified
Solubility Practically insoluble in cold water
Log Pow 3.04
Viscosity, kinematic Not specified
Viscosity, dynamic Not specified
Explosive properties Not explosive
Oxidising properties Not oxidizing
Explosive limits Not specified
SECTION 10: Stability and reactivity
10.1 Reactivity
Reactivity Stable under normal conditions; avoid strong oxidizing agents.
10.2 Chemical stability
Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
Possibility of hazardous reactions No dangerous reactions known under normal conditions of use.
10.4 Conditions to avoid
Conditions to avoid Avoid contact with incompatible materials and excessive heat.
10.5 Incompatible materials
Incompatible materials Strong oxidizing agents, strong acids, and bases.
10.6 Hazardous decomposition products
Hazardous decomposition products When heated to decomposition it emits toxic fumes of nitrogen oxides.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Mouse oral >2500 mg/kg; LD50 Mouse oral 47200 ug/kg; LD50 Rat ip 9500 ug/kg
Skin corrosion/irritation H315: Causes skin irritation
Serious eye damage/irritation H318: Causes serious eye damage
Respiratory or skin sensitisation Not classified (based on available data)
Germ cell mutagenicity Not classified (based on available data)
Carcinogenicity Not classified (based on available data)
Specific target organ toxicity (single exposure) Not classified (based on available data)
Specific target organ toxicity (repeated exposure) Not classified (based on available data)
SECTION 12: Ecological information
12.1 Toxicity
Toxicity information Not specified
12.2 Persistence - degradability
Persistence - degradability Not specified
12.3 Bioaccumulative potential
Bioaccumulative potential Not specified
12.4 Mobility in soil
Mobility in soil Not specified
12.6 Other adverse effects
Environmental precautions Not specified
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Additional Info Dispose of contents/container in accordance with local, regional, national and international regulations.
SECTION 14: Transport information
14.1 UN number
UN-No. (ADR) UN 1544
UN-No. (IMDG) UN 1544
UN-No. (IATA) UN 1544
UN-No. (ADN) UN 1544
UN-No. (RID) UN 1544
14.2 UN proper shipping name
Proper Shipping Name (ADR) Capsaicin
Proper Shipping Name (IMDG) Capsaicin
Proper Shipping Name (IATA) Capsaicin
Proper Shipping Name (ADN) Capsaicin
Proper Shipping Name (RID) Capsaicin
14.3 Transport hazard class(es)
Transport hazard class(es) 6.1
14.4 Packing group
Packing group (ADR) III
Packing group (IMDG) III
Packing group (IATA) III
Packing group (ADN) III
Packing group (RID) III
14.5 Environmental hazards
Dangerous for the environment Not specified
Marine pollutant Not specified
Other information No supplementary information available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations Not specified
SECTION 16: Other Information
Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.