Cyanogen bromide
Synonyms: Cyanobromide
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical Name
Cyanogen bromide
Product Form
Substance
Catalogue No.
AL1578
CAS Number
506-68-3
EC Number
208-051-2
EC Index Number
-
Grade
99% For Synthesis
HSN Code
28530091
Molecular Formula
BrCN
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name
Cyanogen bromide
Catalogue No.
AL1578
Product form
Substance
CAS Number
506-68-3
EC Number
208-051-2
Grade
99% For Synthesis
EC Index Number
Not specified
Chemical Formula
BrCN
HSN Code
28530091
Synonyms
Cyanobromide
Chemical Structure
-
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture
Reagent for protein cleavage and polysaccharide activation.
Uses advised against
Not specified
1.3 Details of the supplier of the safety data sheet
Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute Tox. 2; Skin Corr. 1B; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1
Classification source
ECHA C&L Inventory via PubChem CID 10476 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 Label elements
Hazard pictograms
Corrosive, Acute Toxic, Environmental Hazard
Signal word
Danger
Hazard statements
H300+H310+H330: Fatal if swallowed, in contact with skin or if inhaled; H300: Fatal if swallowed; H310: Fatal in contact with skin; H314: Causes severe skin burns and eye damage; H318: Causes serious eye damage; H330: Fatal if inhaled; H400: Very toxic to aquatic life; H410: Very toxic to aquatic life with long lasting effects
Precautionary statements
P260, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P320, P321, P330, P361+P364, P363, P391, P403+P233, P405, P501
2.3 Other hazards
Other hazards
Extremely toxic; releases cyanide upon hydrolysis.
SECTION 3: Composition/information on ingredients
3.1 Substance
Name
Cyanogen bromide
CAS No.
506-68-3
SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation
Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention immediately.
First-aid measures after skin contact
Remove contaminated clothing. Wash skin with soap and water. Seek medical attention if irritation persists.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Seek medical attention immediately.
First-aid measures after ingestion
Do not induce vomiting. Rinse mouth and seek medical attention immediately.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use
Toxic effects may include headache, dizziness, nausea, and respiratory distress.
4.3 Indication of any immediate medical attention and special treatment needed
General information
Treat symptomatically. Show this safety data sheet to the treating physician.
SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified
5.2 Special hazards arising from the substance or mixture
Special procedures
The vapour is heavier than air.
5.3 Advice for firefighters
Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.
SECTION 6: Accidental release measures
6.1.1 For non-emergency personnel
Emergency procedures
Evacuate area and ventilate. Wear appropriate protective equipment. Contain and neutralize spill.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers.
6.4 Reference to other sections
Reference
Not specified
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling
Handle under a fume hood with appropriate PPE. Avoid contact with skin and eyes.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed.
SECTION 8: Exposure controls/personal protection
8.2 Exposure controls
Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use a NIOSH-approved respirator if exposure limits are exceeded.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state
Solid
Colour
White
Odour
Penetrating
Odour threshold
Not specified
pH value
Not applicable
Relative evaporation rate (butylacetate=1)
Not specified
Melting point
52 °C
Freezing point
Not specified
Boiling point
61.5 °C
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
Not specified
Flammability (solid, gas)
Not flammable under normal conditions
Vapour pressure
Vapor pressure = 115.6 mm Hg at 25 C extrapolated
Relative vapour density at 20°C
3.62 (Air = 1)
Density
2.015 g/cu cm at 20 °C
Solubility
In water, soluble with hydrolysis
Log Pow
Not specified
Viscosity, kinematic
Not specified
Viscosity, dynamic
Not specified
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not applicable
SECTION 10: Stability and reactivity
10.1 Reactivity
Reactivity
Reacts violently with water, releasing toxic gases.
10.2 Chemical stability
Chemical stability
Cyanogen bromide is moderately endothermic & shows evidence of instability.
10.3 Possibility of hazardous reactions
Possibility of hazardous reactions
Decomposes on heating and on contact with acids. This produces highly toxic and flammable hydrogen cyanide (see ICSC 0492) and corrosive hydrogen bromide (see ICSC 0282). Reacts with strong oxidants.
10.4 Conditions to avoid
Conditions to avoid
Avoid contact with incompatible materials and excessive heat.
10.5 Incompatible materials
Incompatible materials
Strong oxidizers, strong acids, and bases.
10.6 Hazardous decomposition products
Hazardous decomposition products
If involved in a fire decomposes to produce toxic gases.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
LD50 (oral, rat) 10 mg/kg; highly toxic.
Skin corrosion/irritation
H314: Causes severe skin burns and eye damage
Serious eye damage/irritation
H318: Causes serious eye damage
Respiratory or skin sensitisation
Not classified (based on available data)
Germ cell mutagenicity
Not classified (based on available data)
Carcinogenicity
Not classified (based on available data)
Specific target organ toxicity (single exposure)
Not classified (based on available data)
Specific target organ toxicity (repeated exposure)
Not classified (based on available data)
SECTION 12: Ecological information
12.1 Toxicity
Toxicity information
Not specified
12.2 Persistence - degradability
Persistence - degradability
Not specified
12.3 Bioaccumulative potential
Bioaccumulative potential
Not specified
12.4 Mobility in soil
Mobility in soil
Not specified
12.6 Other adverse effects
Environmental precautions
Not specified
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.
SECTION 14: Transport information
14.1 UN number
UN-No. (ADR)
UN 1889
UN-No. (IMDG)
UN 1889
UN-No. (IATA)
UN 1889
UN-No. (ADN)
UN 1889
UN-No. (RID)
UN 1889
14.2 UN proper shipping name
Proper Shipping Name (ADR)
Cyanogen bromide
Proper Shipping Name (IMDG)
Cyanogen bromide
Proper Shipping Name (IATA)
Cyanogen bromide
Proper Shipping Name (ADN)
Cyanogen bromide
Proper Shipping Name (RID)
Cyanogen bromide
14.3 Transport hazard class(es)
Transport hazard class(es)
6.1 (8)
14.4 Packing group
Packing group (ADR)
I
Packing group (IMDG)
I
Packing group (IATA)
I
Packing group (ADN)
I
Packing group (RID)
I
14.5 Environmental hazards
Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations
Not specified
SECTION 16: Other Information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.