Dimethylformamide
Synonyms: N,N-Dimethylformamide, DMF
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical Name
Dimethylformamide
Product Form
Substance
Catalogue No.
AL1844
CAS Number
68-12-2
EC Number
200-679-5
EC Index Number
-
Grade
For Molecular Biology
HSN Code
29242990
Molecular Formula
C3H7NO
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name
Dimethylformamide
Catalogue No.
AL1844
Product form
Substance
CAS Number
68-12-2
EC Number
200-679-5
Grade
For Molecular Biology
EC Index Number
Not specified
Chemical Formula
C3H7NO
HSN Code
29242990
Synonyms
N,N-Dimethylformamide, DMF
Chemical Structure
-
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture
Solvent for chemical reactions and oligonucleotide synthesis.
Uses advised against
Not specified
1.3 Details of the supplier of the safety data sheet
Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute Tox. 4; Eye Irrit. 2; Repr. 1B
Classification source
ECHA C&L Inventory via PubChem CID 6228 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 Label elements
Hazard pictograms
Irritant, Health Hazard
Signal word
Danger
Hazard statements
H312: Harmful in contact with skin; H319: Causes serious eye irritation; H332: Harmful if inhaled; H360: May damage fertility or the unborn child
2.3 Other hazards
Other hazards
Reproductive toxicity, may cause harm to the unborn child.
SECTION 3: Composition/information on ingredients
3.1 Substance
Name
Dimethylformamide
CAS No.
68-12-2
SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation
If this chemical has been inhaled, remove the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the person warm and at rest.
First-aid measures after skin contact
If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.
First-aid measures after eye contact
If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.
First-aid measures after ingestion
If this chemical has been swallowed, get medical attention immediately.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use
Headache, dizziness, nausea, skin irritation.
4.3 Indication of any immediate medical attention and special treatment needed
General information
Treat symptomatically. Show this safety data sheet to the treating physician.
SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable extinguishing media
Not specified
5.2 Special hazards arising from the substance or mixture
Special procedures
Flammable liquid; may produce toxic fumes in a fire.
5.3 Advice for firefighters
Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.
SECTION 6: Accidental release measures
6.1.1 For non-emergency personnel
Emergency procedures
Evacuate area. Contain spill and absorb with inert material.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up
Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible.
6.4 Reference to other sections
Reference
Not specified
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling
Use in a fume hood. Wear appropriate personal protective equipment (PPE).
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Separated from incompatible materials. See Chemical Dangers.
SECTION 8: Exposure controls/personal protection
8.2 Exposure controls
Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use appropriate respiratory protection if ventilation is inadequate.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state
Liquid
Colour
Colorless
Odour
Fishy odor
Odour threshold
Not specified
pH value
Not specified
Relative evaporation rate (butylacetate=1)
Not specified
Melting point
-60.3 °C
Freezing point
Not specified
Boiling point
152.8 °C
Flash point
67 °C (open cup); 58 °C (Closed cup)
Auto-ignition temperature
440 °C
Decomposition temperature
Not specified
Flammability (solid, gas)
Flammable liquid
Vapour pressure
3.87 mm Hg at 25 °C
Relative vapour density at 20°C
2.51 (Air= 1)
Density
0.9445 at 25 °C/4 °C
Solubility
Miscible with water and most common organic solvents
Log Pow
-1.01
Viscosity, kinematic
Not specified
Viscosity, dynamic
0.92 mPa·s at 20 °C
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not specified
SECTION 10: Stability and reactivity
10.1 Reactivity
Reactivity
Stable under normal conditions. Reacts with strong oxidizing agents.
10.2 Chemical stability
Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
Possibility of hazardous reactions
Decomposes on heating. This produces toxic fumes including nitrogen oxides. Reacts violently with strong oxidants, halogens, halogenated hydrocarbons and nitrates.
10.4 Conditions to avoid
Conditions to avoid
Avoid contact with incompatible materials and excessive heat.
10.5 Incompatible materials
Incompatible materials
Strong oxidizing agents, strong acids, and bases.
10.6 Hazardous decomposition products
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of nitrogen oxides.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
LD50 Mouse oral 6.8 mL/kg; LD50 MOUSE IP 1120 MGKG (1.2 MLKG); LD50 Swiss mouse ip 3.07 g/kg daily for 21 days
Skin corrosion/irritation
Not classified (based on available data)
Serious eye damage/irritation
H319: Causes serious eye irritation
Respiratory or skin sensitisation
Not classified (based on available data)
Germ cell mutagenicity
Not classified (based on available data)
Carcinogenicity
Not classified (based on available data)
Specific target organ toxicity (single exposure)
Not classified (based on available data)
Specific target organ toxicity (repeated exposure)
Not classified (based on available data)
SECTION 12: Ecological information
12.1 Toxicity
Toxicity information
Not specified
12.2 Persistence - degradability
Persistence - degradability
Not specified
12.3 Bioaccumulative potential
Bioaccumulative potential
Not specified
12.4 Mobility in soil
Mobility in soil
Not specified
12.6 Other adverse effects
Environmental precautions
Not specified
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.
SECTION 14: Transport information
14.1 UN number
UN-No. (ADR)
UN 2265
UN-No. (IMDG)
UN 2265
UN-No. (IATA)
UN 2265
UN-No. (ADN)
UN 2265
UN-No. (RID)
UN 2265
14.2 UN proper shipping name
Proper Shipping Name (ADR)
Dimethylformamide
Proper Shipping Name (IMDG)
Dimethylformamide
Proper Shipping Name (IATA)
Dimethylformamide
Proper Shipping Name (ADN)
Dimethylformamide
Proper Shipping Name (RID)
Dimethylformamide
14.3 Transport hazard class(es)
Transport hazard class(es)
3
14.4 Packing group
Packing group (ADR)
III
Packing group (IMDG)
III
Packing group (IATA)
III
Packing group (ADN)
III
Packing group (RID)
III
14.5 Environmental hazards
Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations
Not specified
SECTION 16: Other Information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.