Dimethyl sulfate
Synonyms: Methyl sulfate, Dimethylsulfate
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical Name
Dimethyl sulfate
Product Form
Substance
Catalogue No.
AL1874
CAS Number
77-78-1
EC Number
201-058-1
EC Index Number
-
Grade
99% For Synthesis
HSN Code
29209099
Molecular Formula
(CH3O)2SO2
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name
Dimethyl sulfate
Catalogue No.
AL1874
Product form
Substance
CAS Number
77-78-1
EC Number
201-058-1
Grade
99% For Synthesis
EC Index Number
Not specified
Chemical Formula
(CH3O)2SO2
HSN Code
29209099
Synonyms
Methyl sulfate, Dimethylsulfate
Chemical Structure
-
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture
Methylating agent in organic synthesis
Uses advised against
Not specified
1.3 Details of the supplier of the safety data sheet
Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1; Acute Tox. 2; STOT SE 3; Muta. 2; Carc. 1B
Classification source
ECHA C&L Inventory via PubChem CID 6497 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 Label elements
Hazard pictograms
Corrosive, Acute Toxic, Health Hazard
Signal word
Danger
Hazard statements
H301: Toxic if swallowed; H314: Causes severe skin burns and eye damage; H317: May cause an allergic skin reaction; H330: Fatal if inhaled; H335: May cause respiratory irritation; H341: Suspected of causing genetic defects; H350: May cause cancer
2.3 Other hazards
Other hazards
Corrosive to metals, may cause severe burns.
SECTION 3: Composition/information on ingredients
3.1 Substance
Name
Dimethyl sulfate
CAS No.
77-78-1
SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation
If this chemical has been inhaled, remove the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the person warm and at rest.
First-aid measures after skin contact
If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.
First-aid measures after eye contact
If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.
First-aid measures after ingestion
If this chemical has been swallowed, get medical attention immediately.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use
Coughing, shortness of breath, skin burns, eye irritation.
4.3 Indication of any immediate medical attention and special treatment needed
General information
Treat symptomatically. Show this safety data sheet to the treating physician.
SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified
5.2 Special hazards arising from the substance or mixture
Special procedures
May emit toxic fumes under fire conditions. Use water spray to cool containers.
5.3 Advice for firefighters
Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.
SECTION 6: Accidental release measures
6.1.1 For non-emergency personnel
Emergency procedures
Evacuate area. Wear appropriate protective equipment. Contain and absorb spill with inert material.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers.
6.4 Reference to other sections
Reference
Not specified
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling
Use only in a fume hood with appropriate PPE. Avoid contact with skin and eyes.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Dry. Well closed. Ventilation along the floor. Store in an area without drain or sewer access.
SECTION 8: Exposure controls/personal protection
8.2 Exposure controls
Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use a NIOSH-approved respirator if exposure limits are exceeded.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state
Liquid
Colour
Colorless to pale yellow
Odour
Essentially odorless
Odour threshold
Not specified
pH value
Not applicable
Relative evaporation rate (butylacetate=1)
Not specified
Melting point
-27 °C
Freezing point
Not specified
Boiling point
About 188 °C with decomposition
Flash point
182 °F (83 °C) (open cup)
Auto-ignition temperature
370 °F (188 °C)
Decomposition temperature
Not specified
Flammability (solid, gas)
Not flammable
Vapour pressure
0.677 mm Hg at 25 °C
Relative vapour density at 20°C
4.35 (Air = 1)
Density
1.3322 gcu cm at 20 °C4 °C
Solubility
Sol in ether, dioxane, acetone, aromatic hydrocarbons.
Log Pow
0.16
Viscosity, kinematic
Not specified
Viscosity, dynamic
Not specified
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not applicable
SECTION 10: Stability and reactivity
10.1 Reactivity
Reactivity
Reacts violently with strong bases and nucleophiles.
10.2 Chemical stability
Chemical stability
Stable at room temperature.
10.3 Possibility of hazardous reactions
Possibility of hazardous reactions
Decomposes on heating and on burning. This produces toxic fumes including sulfur oxides. The solution is a medium strong acid.
10.4 Conditions to avoid
Conditions to avoid
Avoid contact with incompatible materials and excessive heat.
10.5 Incompatible materials
Incompatible materials
Strong bases, strong oxidizers, amines, and alcohols.
10.6 Hazardous decomposition products
Hazardous decomposition products
Not specified
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
LC50 Guinea pig inhalation 167 mgcu m (32 ppm)60 min.; LC50 Mouse inhalation 513 mgcu m (98 ppm)60 min.; LC50 Mouse inhalation 280 mgcu m4 hr.
Skin corrosion/irritation
H314: Causes severe skin burns and eye damage
Serious eye damage/irritation
Not classified (based on available data)
Respiratory or skin sensitisation
H317: May cause an allergic skin reaction
Germ cell mutagenicity
H341: Suspected of causing genetic defects
Carcinogenicity
H350: May cause cancer
Specific target organ toxicity (single exposure)
H335: May cause respiratory irritation
Specific target organ toxicity (repeated exposure)
Not classified (based on available data)
SECTION 12: Ecological information
12.1 Toxicity
Toxicity information
Not specified
12.2 Persistence - degradability
Persistence - degradability
Not specified
12.3 Bioaccumulative potential
Bioaccumulative potential
Not specified
12.4 Mobility in soil
Mobility in soil
Not specified
12.6 Other adverse effects
Environmental precautions
Not specified
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.
SECTION 14: Transport information
14.1 UN number
UN-No. (ADR)
UN 1595
UN-No. (IMDG)
UN 1595
UN-No. (IATA)
UN 1595
UN-No. (ADN)
UN 1595
UN-No. (RID)
UN 1595
14.2 UN proper shipping name
Proper Shipping Name (ADR)
Dimethyl sulfate
Proper Shipping Name (IMDG)
Dimethyl sulfate
Proper Shipping Name (IATA)
Dimethyl sulfate
Proper Shipping Name (ADN)
Dimethyl sulfate
Proper Shipping Name (RID)
Dimethyl sulfate
14.3 Transport hazard class(es)
Transport hazard class(es)
6.1 (8)
14.4 Packing group
Packing group (ADR)
I
Packing group (IMDG)
I
Packing group (IATA)
I
Packing group (ADN)
I
Packing group (RID)
I
14.5 Environmental hazards
Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations
Not specified
SECTION 16: Other Information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.