Safety Data Sheet - Ethyl Chloroformate

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Chemical Name Ethyl Chloroformate

Product Form Substance

Catalogue No. AL2065

CAS Number 541-41-3

EC Number 208-778-5

EC Index Number 607-007-00-8

Grade 97% For Synthesis

HSN Code 29153990

Molecular Formula C3H5ClO2

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier

Chemical Name Ethyl Chloroformate

Catalogue No. AL2065

Product form Substance

CAS Number 541-41-3

EC Number 208-778-5

Grade 97% For Synthesis

EC Index Number 607-007-00-8

Chemical Formula C3H5ClO2

HSN Code 29153990

Synonyms Ethyl chloroformate, Ethyl chloroformate reagent

Chemical Structure -

1.2 Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture Reagent for organic synthesis, particularly in peptide coupling and ester synthesis.

Uses advised against Not specified

1.3 Details of the supplier of the safety data sheet

Company identification Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 Emergency Contact Details

Phone / e-Mail Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 Flam. Liq. 2; Acute Tox. 3; Skin Corr. 1B; Eye Dam. 1; Acute Tox. 2

Classification source ECHA C&L Inventory via PubChem CID 10928 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements

2.2 Label elements

Hazard pictograms Flammable, Corrosive, Acute Toxic

Signal word Danger

Hazard statements H225: Highly Flammable liquid and vapor; H301: Toxic if swallowed; H314: Causes severe skin burns and eye damage; H318: Causes serious eye damage; H330: Fatal if inhaled

2.3 Other hazards

Other hazards May cause respiratory irritation; may be harmful if inhaled.

SECTION 3: Composition/information on ingredients

3.1 Substance

Name Ethyl Chloroformate

CAS No. 541-41-3

SECTION 4: First aid measures

4.1 Description of first aid measures

First-aid measures after inhalation Remove to fresh air; use artificial respiration if breathing has stopped; call a doctor; keep victim quiet and administer oxygen if needed.

First-aid measures after skin contact Wash liberally with water for at least 15 min., then apply dilute solution of sodium bicarbonate or commercially prepared neutralizer.

First-aid measures after eye contact Flush with water for at least 15 min.; see a doctor.

First-aid measures after ingestion Do NOT induce vomiting; give large amount of water; get medical attention.

4.2 Most important symptoms and effects, both acute and delayed

Symptoms relating to use Coughing, shortness of breath, skin irritation, eye irritation.

4.3 Indication of any immediate medical attention and special treatment needed

General information Treat symptomatically. Show this safety data sheet to the treating physician.

SECTION 5: Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media Water spray, carbon dioxide, dry chemical powder, foam.

Unsuitable extinguishing media Not specified

5.2 Special hazards arising from the substance or mixture

Special procedures Flammable liquid. Vapors are heavier than air & may travel to a source of ignition & flash back.

5.3 Advice for firefighters

Protection during firefighting Do not enter fire area without proper protective equipment, including respiratory protection.

SECTION 6: Accidental release measures

6.1.1 For non-emergency personnel

Emergency procedures Evacuate area. Ventilate. Use appropriate protective equipment. Contain spill.

6.3 Methods and material for containment and cleaning up

Methods for cleaning up Evacuate danger area! Consult an expert! Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible.

6.4 Reference to other sections

Reference Not specified

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Precautions for safe handling Use in a fume hood with appropriate PPE including gloves and goggles.

Hygiene measures Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions Fireproof. Separated from strong oxidants, food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Dry. Well closed.

SECTION 8: Exposure controls/personal protection

8.2 Exposure controls

Hand protection Protective gloves (e.g. nitrile rubber)

Eye protection Chemical safety goggles or safety glasses

Skin and body protection Wear suitable protective clothing

Respiratory protection Use NIOSH-approved respirator if exposure limits are exceeded.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

Physical state Liquid

Colour Colorless to pale yellow

Odour Sharp, like hydrochloric acid

Odour threshold No data available

pH value No data available

Relative evaporation rate (butylacetate=1) No data available

Melting point -80.6 °C

Freezing point No data available

Boiling point 95 °C @ 760 MM HG

Flash point 16 °C

Auto-ignition temperature 932 °F (500 °C)

Decomposition temperature No data available

Flammability (solid, gas) Flammable liquid

Vapour pressure 22.4 mm Hg @ 25 °C

Relative vapour density at 20°C 3.7 (AIR= 1)

Density 1.1403 @ 20 °C/4 °C

Solubility Solubility in water: reaction

Log Pow No data available

Viscosity, kinematic No data available

Viscosity, dynamic No data available

Explosive properties No data available

Oxidising properties No data available

Explosive limits No data available

SECTION 10: Stability and reactivity

10.1 Reactivity

Reactivity Reacts violently with strong bases and oxidizing agents.

10.2 Chemical stability

Chemical stability Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Possibility of hazardous reactions Decomposes on heating. This produces toxic and irritating fumes including hydrogen chloride and phosgene. Reacts with water and steam.

10.4 Conditions to avoid

Conditions to avoid Avoid contact with incompatible materials and excessive heat.

10.5 Incompatible materials

Incompatible materials Strong oxidizers, strong bases, amines, alcohols.

10.6 Hazardous decomposition products

Hazardous decomposition products Not specified

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity Highly toxic; LD50 (oral, rat) 50 mg/kg.

Skin corrosion/irritation H314: Causes severe skin burns and eye damage

Serious eye damage/irritation H318: Causes serious eye damage

Respiratory or skin sensitisation Not classified (based on available data)

Germ cell mutagenicity Not classified (based on available data)

Carcinogenicity Not classified (based on available data)

Specific target organ toxicity (single exposure) Not classified (based on available data)

Specific target organ toxicity (repeated exposure) Not classified (based on available data)

SECTION 12: Ecological information

12.1 Toxicity

Toxicity information Not specified

12.2 Persistence - degradability

Persistence - degradability Not specified

12.3 Bioaccumulative potential

Bioaccumulative potential Not specified

12.4 Mobility in soil

Mobility in soil Not specified

12.6 Other adverse effects

Environmental precautions Not specified

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Additional Info Dispose of contents/container in accordance with local, regional, national and international regulations.

SECTION 14: Transport information

14.1 UN number

UN-No. (ADR) UN 1182

UN-No. (IMDG) UN 1182

UN-No. (IATA) UN 1182

UN-No. (ADN) UN 1182

UN-No. (RID) UN 1182

14.2 UN proper shipping name

Proper Shipping Name (ADR) Ethyl Chloroformate

Proper Shipping Name (IMDG) Ethyl Chloroformate

Proper Shipping Name (IATA) Ethyl Chloroformate

Proper Shipping Name (ADN) Ethyl Chloroformate

Proper Shipping Name (RID) Ethyl Chloroformate

14.3 Transport hazard class(es)

Transport hazard class(es) 6.1 (3, 8)

14.4 Packing group

Packing group (ADR) I

Packing group (IMDG) I

Packing group (IATA) I

Packing group (ADN) I

Packing group (RID) I

14.5 Environmental hazards

Dangerous for the environment Not specified

Marine pollutant Not specified

Other information No supplementary information available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations Not specified

SECTION 16: Other Information

Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.