Formamide
Synonyms: Methanamide, N-formylmethanamine
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical Name
Formamide
Product Form
Substance
Catalogue No.
AL2225
CAS Number
75-12-7
EC Number
200-842-0
EC Index Number
612-001-00-7
Grade
For Molecular Biology
HSN Code
29242990
Molecular Formula
CONH3
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name
Formamide
Catalogue No.
AL2225
Product form
Substance
CAS Number
75-12-7
EC Number
200-842-0
Grade
For Molecular Biology
EC Index Number
612-001-00-7
Chemical Formula
CONH3
HSN Code
29242990
Synonyms
Methanamide, N-formylmethanamine
Chemical Structure
-
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture
Nucleic acid denaturant in molecular biology applications.
Uses advised against
Not specified
1.3 Details of the supplier of the safety data sheet
Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Carc. 2; Repr. 1B; STOT RE 2
Classification source
ECHA C&L Inventory via PubChem CID 713 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 Label elements
Hazard pictograms
Health Hazard
Signal word
Danger
Hazard statements
H351: Suspected of causing cancer; H360: May damage fertility or the unborn child; H373: May causes damage to organs through prolonged or repeated exposure
2.3 Other hazards
Other hazards
Reproductive toxicant; handle with gloves.
SECTION 3: Composition/information on ingredients
3.1 Substance
Name
Formamide
CAS No.
75-12-7
SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation
If this chemical has been inhaled, remove the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the person warm and at rest.
First-aid measures after skin contact
If this chemical contacts the skin, wash the contaminated skin with water.
First-aid measures after eye contact
If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.
First-aid measures after ingestion
If this chemical has been swallowed, get medical attention immediately.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use
Headache, dizziness, nausea, and skin irritation.
4.3 Indication of any immediate medical attention and special treatment needed
General information
Treat symptomatically. Show this safety data sheet to the treating physician.
SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified
5.2 Special hazards arising from the substance or mixture
Special procedures
The vapour is heavier than air.
5.3 Advice for firefighters
Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.
SECTION 6: Accidental release measures
6.1.1 For non-emergency personnel
Emergency procedures
Contain spill and absorb with inert material. Dispose of in accordance with local regulations.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Store and dispose of according to local regulations.
6.4 Reference to other sections
Reference
Not specified
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling
Avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Separated from oxidants, acids and bases. Dry.
SECTION 8: Exposure controls/personal protection
8.2 Exposure controls
Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use appropriate respiratory protection if ventilation is inadequate.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state
Liquid
Colour
Colorless to pale yellow
Odour
Faint ammonia odor
Odour threshold
Not established
pH value
Not applicable
Relative evaporation rate (butylacetate=1)
<1
Melting point
2.55 °C
Freezing point
-1.0 °C
Boiling point
210.5 °C @ 760 mm Hg
Flash point
154 °C
Auto-ignition temperature
>500 °C
Decomposition temperature
Not established
Flammability (solid, gas)
Not flammable
Vapour pressure
6.10X10-2 mm Hg @ 25 °C
Relative vapour density at 20°C
1.56 (Air = 1)
Density
1.1334 @ 20 °C/4 °C
Solubility
Sol in alcohol and acetone
Log Pow
log Kow= -1.51
Viscosity, kinematic
Not established
Viscosity, dynamic
1.5 mPa·s at 20 °C
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not applicable
SECTION 10: Stability and reactivity
10.1 Reactivity
Reactivity
Stable under normal conditions; incompatible with strong oxidizing agents.
10.2 Chemical stability
Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
Possibility of hazardous reactions
Decomposes at 180 °C. This produces toxic and corrosive gases including ammonia and hydrogen cyanide. Reacts with oxidants, acids and bases. This generates fire and toxic hazard.
10.4 Conditions to avoid
Conditions to avoid
Avoid contact with incompatible materials and excessive heat.
10.5 Incompatible materials
Incompatible materials
Strong oxidizers, strong acids.
10.6 Hazardous decomposition products
Hazardous decomposition products
Decomposition products at the boiling point are ammonia, water, carbon monoxide and hydrogen cyanide.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
LD50 Rat oral 6 g/kg; LD50 Mouse oral 3.15 g/kg; LD50 Rabbit dermal 6 g/kg
Skin corrosion/irritation
Not classified (based on available data)
Serious eye damage/irritation
Not classified (based on available data)
Respiratory or skin sensitisation
Not classified (based on available data)
Germ cell mutagenicity
Not classified (based on available data)
Carcinogenicity
H351: Suspected of causing cancer
Specific target organ toxicity (single exposure)
Not classified (based on available data)
Specific target organ toxicity (repeated exposure)
H373: May causes damage to organs through prolonged or repeated exposure
SECTION 12: Ecological information
12.1 Toxicity
Toxicity information
Not specified
12.2 Persistence - degradability
Persistence - degradability
Not specified
12.3 Bioaccumulative potential
Bioaccumulative potential
Not specified
12.4 Mobility in soil
Mobility in soil
Not specified
12.6 Other adverse effects
Environmental precautions
Not specified
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.
SECTION 14: Transport information
14.1 UN number
UN-No. (ADR)
Not assigned
UN-No. (IMDG)
Not assigned
UN-No. (IATA)
Not assigned
UN-No. (ADN)
Not assigned
UN-No. (RID)
Not assigned
14.2 UN proper shipping name
Proper Shipping Name (ADR)
Formamide
Proper Shipping Name (IMDG)
Formamide
Proper Shipping Name (IATA)
Formamide
Proper Shipping Name (ADN)
Formamide
Proper Shipping Name (RID)
Formamide
14.3 Transport hazard class(es)
Transport hazard class(es)
Not classified as hazardous
14.4 Packing group
Packing group (ADR)
Not applicable
Packing group (IMDG)
Not applicable
Packing group (IATA)
Not applicable
Packing group (ADN)
Not applicable
Packing group (RID)
Not applicable
14.5 Environmental hazards
Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations
Not specified
SECTION 16: Other Information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.