D-Panthenol

Synonyms: D-Pantothenol, Provitamin B5

SECTION 1: Identification of the substance/mixture and of the company/undertaking
Chemical Name D-Panthenol
Product Form Substance
Catalogue No. AL3398
CAS Number 81-13-0
EC Number 201-327-3
EC Index Number -
Grade Extra Pure
HSN Code 29241900
Molecular Formula C9H19NO4
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name D-Panthenol
Catalogue No. AL3398
Product form Substance
CAS Number 81-13-0
EC Number 201-327-3
Grade Extra Pure
EC Index Number Not applicable
Chemical Formula C9H19NO4
HSN Code 29241900
Synonyms D-Pantothenol, Provitamin B5
Chemical Structure -
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture Moisturizing agent in cosmetics and pharmaceuticals
Uses advised against Not specified
1.3 Details of the supplier of the safety data sheet
Company identification Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 Not classified as hazardous (majority of notifications to the ECHA C&L Inventory)
Classification source ECHA C&L Inventory via PubChem CID 131204 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 Label elements
Hazard pictograms None required
Signal word None
Hazard statements None
2.3 Other hazards
Other hazards None known
SECTION 3: Composition/information on ingredients
3.1 Substance
Name D-Panthenol
CAS No. 81-13-0
SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
First-aid measures after ingestion Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use May cause mild irritation to skin and eyes.
4.3 Indication of any immediate medical attention and special treatment needed
General information Treat symptomatically. Show this safety data sheet to the treating physician.
SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media Not specified
5.2 Special hazards arising from the substance or mixture
Special procedures Combustible material; use appropriate fire extinguishing media.
5.3 Advice for firefighters
Protection during firefighting Do not enter fire area without proper protective equipment, including respiratory protection.
SECTION 6: Accidental release measures
6.1.1 For non-emergency personnel
Emergency procedures Contain spill and absorb with inert material. Dispose of in accordance with local regulations.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up Use appropriate protective equipment. Clean up spills immediately to prevent slipping hazards.
6.4 Reference to other sections
Reference Not specified
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling Avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions Dexpanthenol injection should be protected from freezing & excessive heat.
SECTION 8: Exposure controls/personal protection
8.2 Exposure controls
Hand protection Protective gloves (e.g. nitrile rubber)
Eye protection Chemical safety goggles or safety glasses
Skin and body protection Wear suitable protective clothing
Respiratory protection Not required under normal conditions of use.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state Liquid
Colour Colorless to pale yellow
Odour Mild
Odour threshold Not applicable
pH value 5.0 - 7.0
Relative evaporation rate (butylacetate=1) Not determined
Melting point Not applicable
Freezing point Not applicable
Boiling point BP: 118-120 °C at 0.02 mm Hg; somewhat hygroscopic; easily decomposes on
Flash point > 100 °C
Auto-ignition temperature Not determined
Decomposition temperature Not determined
Flammability (solid, gas) Not flammable
Vapour pressure Not determined
Relative vapour density at 20°C Not determined
Density 1.2 at 20 °C/20 °C
Solubility Freely soluble in methanol, water, alcohol; slightly soluble in ether
Log Pow Not determined
Viscosity, kinematic Not determined
Viscosity, dynamic Not determined
Explosive properties Not explosive
Oxidising properties Not oxidizing
Explosive limits Not applicable
SECTION 10: Stability and reactivity
10.1 Reactivity
Reactivity Stable under normal conditions.
10.2 Chemical stability
Chemical stability Reasonably stable to usual sterilization time and temp in aqueous solution at pH 3.0-4.0; long heating causes racemization.
10.3 Possibility of hazardous reactions
Possibility of hazardous reactions No dangerous reactions known under normal conditions of use.
10.4 Conditions to avoid
Conditions to avoid Avoid contact with incompatible materials and excessive heat.
10.5 Incompatible materials
Incompatible materials Strong oxidizing agents.
10.6 Hazardous decomposition products
Hazardous decomposition products When heated to decomposition it emits toxic fumes of nitric oxide.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity LD50 Mouse oral 15,000 mg/kg; LD50 Mouse ip 9,000 mg/kg; LD50 Mouse iv 7000mg/kg
Skin corrosion/irritation Not classified (based on available data)
Serious eye damage/irritation Not classified (based on available data)
Respiratory or skin sensitisation Not classified (based on available data)
Germ cell mutagenicity Not classified (based on available data)
Carcinogenicity Not classified (based on available data)
Specific target organ toxicity (single exposure) Not classified (based on available data)
Specific target organ toxicity (repeated exposure) Not classified (based on available data)
SECTION 12: Ecological information
12.1 Toxicity
Toxicity information Not specified
12.2 Persistence - degradability
Persistence - degradability Not specified
12.3 Bioaccumulative potential
Bioaccumulative potential Not specified
12.4 Mobility in soil
Mobility in soil Not specified
12.6 Other adverse effects
Environmental precautions Not specified
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Additional Info Dispose of contents/container in accordance with local, regional, national and international regulations.
SECTION 14: Transport information
14.1 UN number
UN-No. (ADR) Not applicable
UN-No. (IMDG) Not applicable
UN-No. (IATA) Not applicable
UN-No. (ADN) Not applicable
UN-No. (RID) Not applicable
14.2 UN proper shipping name
Proper Shipping Name (ADR) Not classified as dangerous goods
Proper Shipping Name (IMDG) Not classified as dangerous goods
Proper Shipping Name (IATA) Not classified as dangerous goods
Proper Shipping Name (ADN) Not classified as dangerous goods
Proper Shipping Name (RID) Not classified as dangerous goods
14.3 Transport hazard class(es)
Transport hazard class(es) Not applicable
14.4 Packing group
Packing group (ADR) Not applicable
Packing group (IMDG) Not applicable
Packing group (IATA) Not applicable
Packing group (ADN) Not applicable
Packing group (RID) Not applicable
14.5 Environmental hazards
Dangerous for the environment Not specified
Marine pollutant Not specified
Other information No supplementary information available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations Not specified
SECTION 16: Other Information
Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.