Safety Data Sheet - Piperazine

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Chemical Name Piperazine

Product Form Substance

Catalogue No. AL02472

CAS Number 110-85-0

EC Number 203-808-3

EC Index Number 612-002-00-4

Grade 98% For Synthesis

HSN Code 29335990

Molecular Formula C4H10N2

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier

Chemical Name Piperazine

Catalogue No. AL02472

Product form Substance

CAS Number 110-85-0

EC Number 203-808-3

Grade 98% For Synthesis

EC Index Number 612-002-00-4

Chemical Formula C4H10N2

HSN Code 29335990

Synonyms 1,4-Diazacyclohexane

Chemical Structure -

1.2 Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture Pharmaceutical synthesis

Uses advised against Not specified

1.3 Details of the supplier of the safety data sheet

Company identification Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 Emergency Contact Details

Phone / e-Mail Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 Skin Corr. 1B; Skin Sens. 1B; Resp. Sens. 1B; Repr. 2

Classification source ECHA C&L Inventory via PubChem CID 4837 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements

2.2 Label elements

Hazard pictograms Corrosive, Health Hazard

Signal word Danger

Hazard statements H314: Causes severe skin burns and eye damage; H317: May cause an allergic skin reaction; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled; H361: Suspected of damaging fertility or the unborn child

2.3 Other hazards

Other hazards Hygroscopic; may cause skin and eye irritation.

SECTION 3: Composition/information on ingredients

3.1 Substance

Name Piperazine

CAS No. 110-85-0

SECTION 4: First aid measures

4.1 Description of first aid measures

First-aid measures after inhalation Move to fresh air. If symptoms persist, seek medical attention.

First-aid measures after skin contact IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water.

First-aid measures after eye contact First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

First-aid measures after ingestion Rinse mouth. Do not induce vomiting. Seek medical attention immediately.

4.2 Most important symptoms and effects, both acute and delayed

Symptoms relating to use Irritation of the respiratory tract, skin, and eyes.

4.3 Indication of any immediate medical attention and special treatment needed

General information Treat symptomatically. Show this safety data sheet to the treating physician.

SECTION 5: Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media Water spray, carbon dioxide, dry chemical powder, foam.

Unsuitable extinguishing media Not specified

5.2 Special hazards arising from the substance or mixture

Special procedures May emit toxic fumes under fire conditions.

5.3 Advice for firefighters

Protection during firefighting Do not enter fire area without proper protective equipment, including respiratory protection.

SECTION 6: Accidental release measures

6.1.1 For non-emergency personnel

Emergency procedures Evacuate area and ventilate. Wear appropriate protective equipment.

6.3 Methods and material for containment and cleaning up

Methods for cleaning up Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Ventilation. Sweep spilled substance into covered containers.

6.4 Reference to other sections

Reference Not specified

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Precautions for safe handling Use gloves and safety goggles. Avoid contact with skin and eyes.

Hygiene measures Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions Separated from strong acids, strong oxidants, acid anhydrides, metals and food and feedstuffs. Dry. Well closed.

SECTION 8: Exposure controls/personal protection

8.2 Exposure controls

Hand protection Protective gloves (e.g. nitrile rubber)

Eye protection Chemical safety goggles or safety glasses

Skin and body protection Wear suitable protective clothing

Respiratory protection Use appropriate respiratory protection if ventilation is inadequate.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

Physical state Solid

Colour White

Odour Typical amine odor

Odour threshold Not specified

pH value Not applicable

Relative evaporation rate (butylacetate=1) Not specified

Melting point 106 °C

Freezing point Not specified

Boiling point 146 °C

Flash point 107 °C (Cleveland Open Cup)

Auto-ignition temperature 320 °C

Decomposition temperature Not specified

Flammability (solid, gas) Not flammable

Vapour pressure Vapor pressure = 2.6372X10+4 Pa @ 379.15 deg K

Relative vapour density at 20°C 3.0 (air = 1)

Density 1.1 g/cu cm

Solubility Mol wt 184.13. Minute crystals. Very slightly sol in water. pH of saturated aq soln 6.5

Log Pow -1.50

Viscosity, kinematic Not specified

Viscosity, dynamic Not specified

Explosive properties Not explosive

Oxidising properties Not oxidizing

Explosive limits Not specified

SECTION 10: Stability and reactivity

10.1 Reactivity

Reactivity Stable under normal conditions, but may react with strong oxidizing agents.

10.2 Chemical stability

Chemical stability Stable at temperatures to 270 °C and in neutral or acid media.

10.3 Possibility of hazardous reactions

Possibility of hazardous reactions Decomposes on burning. This produces toxic and corrosive gases including nitrogen oxides. The solution in water is a medium strong base.

10.4 Conditions to avoid

Conditions to avoid Avoid contact with incompatible materials and excessive heat.

10.5 Incompatible materials

Incompatible materials Strong oxidizers, acids.

10.6 Hazardous decomposition products

Hazardous decomposition products When heated to decomposition it emits highly toxic fumes of nitrogen oxide.

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity LD50 Rat oral 4,900 mg/kg; LD50 Rat oral 2,050 mg/kg; LD50 Mouse oral 6,200 mg/kg

Skin corrosion/irritation H314: Causes severe skin burns and eye damage

Serious eye damage/irritation Not classified (based on available data)

Respiratory or skin sensitisation H317: May cause an allergic skin reaction; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled

Germ cell mutagenicity Not classified (based on available data)

Carcinogenicity Not classified (based on available data)

Specific target organ toxicity (single exposure) Not classified (based on available data)

Specific target organ toxicity (repeated exposure) Not classified (based on available data)

SECTION 12: Ecological information

12.1 Toxicity

Toxicity information Not specified

12.2 Persistence - degradability

Persistence - degradability Not specified

12.3 Bioaccumulative potential

Bioaccumulative potential Not specified

12.4 Mobility in soil

Mobility in soil Not specified

12.6 Other adverse effects

Environmental precautions Not specified

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Additional Info Dispose of contents/container in accordance with local, regional, national and international regulations.

SECTION 14: Transport information

14.1 UN number

UN-No. (ADR) 2579

UN-No. (IMDG) 2579

UN-No. (IATA) 2579

UN-No. (ADN) 2579

UN-No. (RID) 2579

14.2 UN proper shipping name

Proper Shipping Name (ADR) Piperazine

Proper Shipping Name (IMDG) Piperazine

Proper Shipping Name (IATA) Piperazine

Proper Shipping Name (ADN) Piperazine

Proper Shipping Name (RID) Piperazine

14.3 Transport hazard class(es)

Transport hazard class(es) 8

14.4 Packing group

Packing group (ADR) III

Packing group (IMDG) III

Packing group (IATA) III

Packing group (ADN) III

Packing group (RID) III

14.5 Environmental hazards

Dangerous for the environment Not specified

Marine pollutant Not specified

Other information No supplementary information available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations Not specified

SECTION 16: Other Information

Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a guarantee or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.