Acetone oxime

99% For Laboratory Use
CAS Number
127-06-0
HSN Code
29280090
Molecular Formula
C3H7NO
Catalogue Number
AL0068
Purity
≥ 99%
Molecular Weight
73.09 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance Columnar prisms
Shelf Life 2 years
Packaging Available in: 10 gm glass bottle, 50 gm glass bottle
Storage Keep container tightly closed in a dry and well-ventilated place.

Acetone oxime (acetoxime) is the oxime derivative of acetone, used as a mild blocking agent for isocyanates and an anti-skinning agent in paints.

Also known as Acetoxime.

Catalogue No.
AL0068
CAS Number
127-06-0
Molecular Formula
C3H7NO
Molecular Weight
73.09 g/mol
HSN Code
29280090
Grade
99%
Product Form
Substance

Melting point: 61 °C; Boiling point: 133 °C; Density: Density: 0.9113 g/cm cu at 62 °C; Solubility: In water, 30.0 to 32.7% w/w at 20.0 °C.

Appearance
Columnar prisms
Shelf Life
2 years
Packaging
Available in: 10 gm glass bottle, 50 gm glass bottle
Storage
Keep container tightly closed in a dry and well-ventilated place.

1.1 — Product identifier

Chemical Name
Acetone oxime
Catalogue No.
AL0068
Product form
Substance
CAS Number
127-06-0
EC Number
204-820-1
Grade
99%
EC Index Number
606-021-00-7
Chemical Formula
C3H7NO
HSN Code
29280090
Synonyms
Acetoxime

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used as a blocking agent for isocyanates and as an anti-skinning agent in paints.
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.1 — Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008
Carc. 1B; Acute Tox. 4; STOT SE 3; STOT RE 2; Eye Dam. 1; Skin Sens. 1
Classification source
CLP Annex VI via PubChem CID 67180

2.2 — Label elements

Hazard pictograms
Corrosive, Irritant, Health Hazard
Signal word
Danger
Hazard statements
H312: Harmful in contact with skin; H317: May cause an allergic skin reaction; H318: Causes serious eye damage; H336: May cause drowsiness or dizziness; H350: May cause cancer; H373: May causes damage to organs through prolonged or repeated exposure
Precautionary statements
P203, P260, P261, P264+P265, P271, P272, P280, P302+P352, P304+P340, P305+P354+P338, P317, P318, P319, P321, P333+P317, P362+P364, P403+P233, P405, P501

2.3 — Other hazards

Other hazards
May form explosive peroxides upon prolonged storage.

3.1 — Substance

Name
Acetone oxime
CAS No.
127-06-0

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
First-aid measures after ingestion
Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
Headache, dizziness, nausea, skin irritation.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary. Further information: Use water spray to cool unopened containers.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Flammable solid; may produce toxic fumes in a fire.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Evacuate area and eliminate all ignition sources. Use appropriate protective equipment.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Sweep up and place in a suitable container for disposal. Avoid generating dust.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Keep container tightly closed in a dry and well-ventilated place.

8.2 — Exposure controls

Hand protection
Handle with gloves.
Eye protection
Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin and body protection
Complete suit protecting against chemicals. Flame retardant antistatic protective clothing.The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Use appropriate respiratory protection if ventilation is inadequate.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White
Odour
Slightly sweet
Odour threshold
No data available
pH value
No data available
Relative evaporation rate (butylacetate=1)
No data available
Melting point
61 °C
Freezing point
No data available
Boiling point
133 °C
Flash point
25 °C
Auto-ignition temperature
No data available
Decomposition temperature
No data available
Flammability (solid, gas)
Flammable solid
Vapour pressure
1.82 mm Hg at 25 °C (242 hPa)
Relative vapour density at 20°C
No data available
Density
Density: 0.9113 g/cm cu at 62 °C
Solubility
In water, 30.0 to 32.7% w/w at 20.0 °C
Log Pow
0.12
Viscosity, kinematic
No data available
Viscosity, dynamic
No data available
Explosive properties
Not explosive
Oxidising properties
Not oxidising
Explosive limits
No data available

10.1 — Reactivity

Reactivity
Stable under normal conditions. Reacts with strong oxidizing agents.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong oxidizers, strong acids, and bases.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx).

11.1 — Information on toxicological effects

Acute toxicity
LD50 Rat oral >500 mg/kg; LD50 Rabbit dermal >1000 mg/kg bw; LD50 Rat i.p. 840 mg/kg bw
Skin corrosion/irritation
Not classified (based on available data)
Serious eye damage/irritation
H318: Causes serious eye damage
Respiratory or skin sensitisation
H317: May cause an allergic skin reaction
Germ cell mutagenicity
Not classified (based on available data)
Carcinogenicity
H350: May cause cancer
Specific target organ toxicity (single exposure)
H336: May cause drowsiness or dizziness
Specific target organ toxicity (repeated exposure)
H373: May causes damage to organs through prolonged or repeated exposure

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
1325
UN-No. (IMDG)
1325
UN-No. (IATA)
1325
UN-No. (ADN)
1325
UN-No. (RID)
1325

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Acetone oxime
Proper Shipping Name (IMDG)
Acetone oxime
Proper Shipping Name (IATA)
Acetone oxime
Proper Shipping Name (ADN)
Acetone oxime
Proper Shipping Name (RID)
Acetone oxime

14.3 — Transport hazard class(es)

Transport hazard class(es)
4.1

14.4 — Packing group

Packing group (ADR)
III
Packing group (IMDG)
III
Packing group (IATA)
III
Packing group (ADN)
III
Packing group (RID)
III

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Used as a protecting agent for isocyanates in organic synthesis and industrially as a paint anti-skinning additive.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL1668A
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
73.09 g/mol
Test Standard Observed
Assay ≥ 99% 99.5%
Melting Point -20 °C -19.5 °C
Moisture Content ≤ 0.5% 0.3%
Residue on Ignition ≤ 0.1% 0.05%
Related Substances No more than 0.5% of any individual impurity 0.2%
Solubility Soluble in water and organic solvents Fully soluble in both water and ethanol.

The above product is expected to comply with 99% grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
99% ≥ 99% m.p. 61 °C; b.p. 133 °C ≤ 0.5% ≤ 0.1% No more than 0.5% of any individual impurity In water, 30.0 to 32.7% w/w at 20.0 °C
View full Technical Data Sheet

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