Dimethylformamide
- CAS Number
- 68-12-2
- HSN Code
- 29242990
- Molecular Formula
- C3H7NO
- Catalogue Number
- AL1838
- Purity
- 99.7%
- Molecular Weight
- 73.09 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
N,N-dimethylformamide is a member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups. It has a role as a geroprotector, a polar aprotic solvent and a hepatotoxic agent.
Also known as N,N-Dimethylformamide, DMF.
- Catalogue No.
- AL1838
- CAS Number
- 68-12-2
- Molecular Formula
- C3H7NO
- Molecular Weight
- 73.09 g/mol
- HSN Code
- 29242990
- Grade
- HPLC & Spectroscopy
- Product Form
- Substance
Melting point: -60.3 °C; Boiling point: 152.8 °C; Flash point: 67 °C (open cup); 58 °C (Closed cup); Density: 0.9445 at 25 °C/4 °C; Solubility: Miscible with water and most common organic solvents.
- Appearance
- Colorless to very slightly yellow liquid
- Shelf Life
- -
- Packaging
- Available in: 500 ml glass bottle with tin cap, 1 Lt glass bottle with tin cap, 2.5 Lt glass bottle with tin cap
- Storage
- Separated from incompatible materials. See Chemical Dangers.
1.1 — Product identifier
- Chemical Name
- Dimethylformamide
- Catalogue No.
- AL1838
- Product form
- Substance
- CAS Number
- 68-12-2
- EC Number
- 200-679-5
- Grade
- HPLC & Spectroscopy
- EC Index Number
- Not specified
- Chemical Formula
- C3H7NO
- HSN Code
- 29242990
- Synonyms
- N,N-Dimethylformamide, DMF
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Solvent for chromatography and peptide synthesis.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Acute Tox. 4; Eye Irrit. 2; Repr. 1B
- Classification source
- ECHA C&L Inventory via PubChem CID 6228 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Irritant, Health Hazard
- Signal word
- Danger
- Hazard statements
- H312: Harmful in contact with skin; H319: Causes serious eye irritation; H332: Harmful if inhaled; H360: May damage fertility or the unborn child
2.3 — Other hazards
- Other hazards
- Reproductive toxicant; may cause harm to the unborn child.
3.1 — Substance
- Name
- Dimethylformamide
- CAS No.
- 68-12-2
4.1 — Description of first aid measures
- First-aid measures after inhalation
- If this chemical has been inhaled, remove the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the person warm and at rest.
- First-aid measures after skin contact
- If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.
- First-aid measures after eye contact
- If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.
- First-aid measures after ingestion
- If this chemical has been swallowed, get medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Headache, dizziness, nausea, and skin irritation.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Flammable liquid; may produce toxic fumes in a fire.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Contain spill and absorb with inert material.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood. Wear appropriate personal protective equipment (PPE).
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Separated from incompatible materials. See Chemical Dangers.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless
- Odour
- Fishy odor
- Odour threshold
- Not specified
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- -60.3 °C
- Freezing point
- Not specified
- Boiling point
- 152.8 °C
- Flash point
- 67 °C (open cup); 58 °C (Closed cup)
- Auto-ignition temperature
- 440 °C
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Flammable liquid
- Vapour pressure
- 3.87 mm Hg at 25 °C
- Relative vapour density at 20°C
- 2.51 (Air= 1)
- Density
- 0.9445 at 25 °C/4 °C
- Solubility
- Miscible with water and most common organic solvents
- Log Pow
- -1.01
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- 0.92 mPa·s at 20 °C
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- 1.8 - 11.5% (v/v) in air
10.1 — Reactivity
- Reactivity
- Stable under normal conditions. Reacts with strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Decomposes on heating. This produces toxic fumes including nitrogen oxides. Reacts violently with strong oxidants, halogens, halogenated hydrocarbons and nitrates.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizers, strong acids, and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- When heated to decomposition it emits toxic fumes of nitrogen oxides.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 Mouse oral 6.8 mL/kg; LD50 MOUSE IP 1120 MGKG (1.2 MLKG); LD50 Swiss mouse ip 3.07 g/kg daily for 21 days
- Skin corrosion/irritation
- Not classified (based on available data)
- Serious eye damage/irritation
- H319: Causes serious eye irritation
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 2265
- UN-No. (IMDG)
- UN 2265
- UN-No. (IATA)
- UN 2265
- UN-No. (ADN)
- UN 2265
- UN-No. (RID)
- UN 2265
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Dimethylformamide
- Proper Shipping Name (IMDG)
- Dimethylformamide
- Proper Shipping Name (IATA)
- Dimethylformamide
- Proper Shipping Name (ADN)
- Dimethylformamide
- Proper Shipping Name (RID)
- Dimethylformamide
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 3
14.4 — Packing group
- Packing group (ADR)
- III
- Packing group (IMDG)
- III
- Packing group (IATA)
- III
- Packing group (ADN)
- III
- Packing group (RID)
- III
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as a high-purity chromatographic and peptide-synthesis solvent.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL02216
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 73.09 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | 99.7% min | 99.8% |
| Water Content | <0.1% | 0.05% |
| Residue on Ignition | <0.01% | 0.005% |
| Related Substances | <0.1% | 0.03% |
| Appearance | Colorless liquid | Colorless liquid |
The above product is expected to comply with HPLC & Spectroscopy grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| HPLC & Spectroscopy | 99.7% | m.p. -60.3 °C; b.p. 152.8 °C | <0.1% | <0.01% | <0.1% | Miscible with water and most common organic solvents |
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