Gamma-butyrolactone
- CAS Number
- 96-48-0
- HSN Code
- 29329900
- Molecular Formula
- C4H6O2
- Catalogue Number
- AL1007
- Purity
- ≥ 99%
- Molecular Weight
- 86.09 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Gamma-butyrolactone is a butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2. It has a role as a metabolite and a neurotoxin.
Also known as GBL.
- Catalogue No.
- AL1007
- CAS Number
- 96-48-0
- Molecular Formula
- C4H6O2
- Molecular Weight
- 86.09 g/mol
- HSN Code
- 29329900
- Grade
- 99% For Synthesis
- Product Form
- Substance
Melting point: -43.53 °C; Boiling point: 204 °C at 760 mm Hg; Flash point: 98 °C; Density: 1.1296 g/cu cm at 20 °C; Solubility: Miscible with alcohol and ether.
- Appearance
- Oily liquid
- Shelf Life
- -
- Packaging
- Available in: 500 ml glass bottle, 2.5 Lt glass bottle
- Storage
- Store only in original container. Separated from acids, alcohols, amines, bases and oxidants. Dry. Well closed. Store in an area without drain or sewer access.
1.1 — Product identifier
- Chemical Name
- Gamma-butyrolactone
- Catalogue No.
- AL1007
- Product form
- Substance
- CAS Number
- 96-48-0
- EC Number
- 202-509-5
- Grade
- 99% For Synthesis
- EC Index Number
- Not specified
- Chemical Formula
- C4H6O2
- HSN Code
- 29329900
- Synonyms
- GBL
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Solvent and synthetic intermediate
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Acute Tox. 4; Eye Dam. 1; STOT SE 3
- Classification source
- ECHA C&L Inventory via PubChem CID 7302 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Corrosive, Irritant
- Signal word
- Danger
- Hazard statements
- H302: Harmful if swallowed; H318: Causes serious eye damage; H336: May cause drowsiness or dizziness
2.3 — Other hazards
- Other hazards
- Controlled precursor in many jurisdictions due to potential misuse.
3.1 — Substance
- Name
- Gamma-butyrolactone
- CAS No.
- 96-48-0
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water.
- First-aid measures after eye contact
- First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Headache, dizziness, nausea, and irritation of the skin and eyes.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Combustible liquid. Vapors may form explosive mixtures with air.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area. Ventilate and contain spill.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a well-ventilated area. Avoid contact with skin and eyes.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store only in original container. Separated from acids, alcohols, amines, bases and oxidants. Dry. Well closed. Store in an area without drain or sewer access.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless to pale yellow
- Odour
- Pleasant odor
- Odour threshold
- Not specified
- pH value
- Not specified
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- -43.53 °C
- Freezing point
- Not specified
- Boiling point
- 204 °C at 760 mm Hg
- Flash point
- 98 °C
- Auto-ignition temperature
- 455 °C
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not applicable
- Vapour pressure
- 4.5X10-1 mm Hg at 25 °C
- Relative vapour density at 20°C
- Relative vapor density (air = 1): 3.0
- Density
- 1.1296 g/cu cm at 20 °C
- Solubility
- Miscible with alcohol and ether.
- Log Pow
- -0.64
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not specified
10.1 — Reactivity
- Reactivity
- Stable under normal conditions. Reacts with strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable at pH 7; rapidly hydrolyzed by bases, slowly hydrolyzed by acids.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Reacts with acids, bases, alcohols, amines and oxidants. This generates fire and explosion hazard. Decomposes on burning.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents, strong acids.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- When heated to decomposition it emits acrid and irritating fumes.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 MOUSE ORAL 1260 MG/KG; LD50 MOUSE IV 880 MG/KG; LD50 MOUSE IP 880 MG/KG
- Skin corrosion/irritation
- Not classified (based on available data)
- Serious eye damage/irritation
- H318: Causes serious eye damage
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- H336: May cause drowsiness or dizziness
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not assigned
- UN-No. (IMDG)
- Not assigned
- UN-No. (IATA)
- Not assigned
- UN-No. (ADN)
- Not assigned
- UN-No. (RID)
- Not assigned
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Not assigned
- Proper Shipping Name (IMDG)
- Not assigned
- Proper Shipping Name (IATA)
- Not assigned
- Proper Shipping Name (ADN)
- Not assigned
- Proper Shipping Name (RID)
- Not assigned
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not assigned
14.4 — Packing group
- Packing group (ADR)
- Not assigned
- Packing group (IMDG)
- Not assigned
- Packing group (IATA)
- Not assigned
- Packing group (ADN)
- Not assigned
- Packing group (RID)
- Not assigned
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as a polar aprotic solvent and as a precursor in pyrrolidone/N-methylpyrrolidone (NMP) synthesis.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL02027
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 86.09 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 99% | 99.5% |
| Moisture Content | ≤ 0.5% | 0.3% |
| Residue on Ignition | ≤ 0.1% | 0.05% |
| Related Substances | None detected | None detected |
| Solubility | Miscible with water | Miscible with water |
The above product is expected to comply with 99% For Synthesis grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 99% For Synthesis | ≥ 99% | m.p. -43.53 °C; b.p. 204 °C at 760 mm Hg | ≤ 0.5% | ≤ 0.1% | None detected | Miscible with alcohol and ether. |
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