Imidazole

1.1 — Product identifier

Chemical Name

Imidazole

Catalogue No.

AL0822K

Product form

Substance

CAS Number

288-32-4

EC Number

206-019-2

Grade

Molecular Biology

EC Index Number

613-021-00-5

Chemical Formula

C3H4N2

HSN Code

29332990

Synonyms

1H-Imidazole

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture

Used in biochemical applications, particularly in protein purification.

Uses advised against

Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification

Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail

Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.1 — Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008

Acute Tox. 4; Skin Corr. 1C; Repr. 1B

Classification source

ECHA C&L Inventory via PubChem CID 795 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements

2.2 — Label elements

Hazard pictograms

Corrosive, Irritant, Health Hazard

Signal word

Danger

Hazard statements

H302: Harmful if swallowed; H314: Causes severe skin burns and eye damage; H360: May damage fertility or the unborn child

2.3 — Other hazards

Other hazards

None identified beyond those listed.

3.1 — Substance

Name

Imidazole

CAS No.

288-32-4

4.1 — Description of first aid measures

First-aid measures after inhalation

Move to fresh air. If symptoms persist, seek medical attention.

First-aid measures after skin contact

Wash with soap and water. If irritation occurs, seek medical attention.

First-aid measures after eye contact

Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.

First-aid measures after ingestion

Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use

Irritation of skin, eyes, and respiratory tract.

4.3 — Indication of any immediate medical attention and special treatment needed

General information

Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Unsuitable extinguishing media

Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures

Dust explosion possible if in powder or granular form, mixed with air.

5.3 — Advice for firefighters

Protection during firefighting

Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures

Contain spill and absorb with inert material. Dispose of in accordance with local regulations.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up

Personal protection: complete protective clothing including self-contained breathing apparatus. Sweep spilled substance into covered containers. Then wash away with plenty of water.

6.4 — Reference to other sections

Reference

Not specified

7.1 — Precautions for safe handling

Precautions for safe handling

Avoid contact with skin and eyes. Use in a well-ventilated area.

Hygiene measures

Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions

Separated from strong acids and food and feedstuffs.

8.2 — Exposure controls

Hand protection

Handle with gloves.

Eye protection

Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin and body protection

Complete suit protecting against chemicals. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Use appropriate respiratory protection if ventilation is inadequate.

9.1 — Information on basic physical and chemical properties

Physical state

Solid

Colour

White

Odour

Amine-like odor

Odour threshold

Not applicable

pH value

Not applicable

Relative evaporation rate (butylacetate=1)

Not applicable

Melting point

89.52 °C

Freezing point

Not applicable

Boiling point

257 °C

Flash point

145 °C (293 °F) - closed cup

Auto-ignition temperature

480 °C

Decomposition temperature

Not applicable

Flammability (solid, gas)

Not flammable

Vapour pressure

Vapor pressure = 0.327 Pa at 25 °C (2.25X10-2 mm Hg at 25 °C)

Relative vapour density at 20°C

Relative vapor density (air = 1): 2.35

Density

Density: 1.0303 g/cu m at 101 °C

Solubility

Very soluble in water

Log Pow

-0.08

Viscosity, kinematic

Not applicable

Viscosity, dynamic

Not applicable

Explosive properties

Not explosive

Oxidising properties

Not oxidizing

Explosive limits

Not applicable

10.1 — Reactivity

Reactivity

Stable under normal conditions. Reacts with strong acids and bases.

10.2 — Chemical stability

Chemical stability

Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions

Decomposes on burning. This produces toxic fumes including nitrogen oxides. The solution in water is a weak base.

10.4 — Conditions to avoid

Conditions to avoid

Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials

Strong oxidizing agents, strong acids, strong bases.

10.6 — Hazardous decomposition products

Hazardous decomposition products

Hazardous decomposition products formed under fire conditions - Carbon oxides, nitrogen oxides (NOx), hydrogen cyanide (hydrocyanic acid).

11.1 — Information on toxicological effects

Acute toxicity

LD50 Rat oral 960-970 mg/kg bw; LD50 Rat oral 220 mg/kg; LD50 Mouse (male) oral 1180 mg/kg bw

Skin corrosion/irritation

H314: Causes severe skin burns and eye damage

Serious eye damage/irritation

Not classified (based on available data)

Respiratory or skin sensitisation

Not classified (based on available data)

Germ cell mutagenicity

Not classified (based on available data)

Carcinogenicity

Not classified (based on available data)

Specific target organ toxicity (single exposure)

Not classified (based on available data)

Specific target organ toxicity (repeated exposure)

Not classified (based on available data)

12.1 — Toxicity

Toxicity information

Not specified

12.2 — Persistence - degradability

Persistence - degradability

Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential

Not specified

12.4 — Mobility in soil

Mobility in soil

Not specified

12.6 — Other adverse effects

Environmental precautions

Not specified

13.1 — Waste treatment methods

Additional Info

Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)

UN 3263

UN-No. (IMDG)

UN 3263

UN-No. (IATA)

UN 3263

UN-No. (ADN)

UN 3263

UN-No. (RID)

UN 3263

14.2 — UN proper shipping name

Proper Shipping Name (ADR)

Imidazole

Proper Shipping Name (IMDG)

Imidazole

Proper Shipping Name (IATA)

Imidazole

Proper Shipping Name (ADN)

Imidazole

Proper Shipping Name (RID)

Imidazole

14.3 — Transport hazard class(es)

Transport hazard class(es)

8

14.4 — Packing group

Packing group (ADR)

III

Packing group (IMDG)

III

Packing group (IATA)

III

Packing group (ADN)

III

Packing group (RID)

III

14.5 — Environmental hazards

Dangerous for the environment

Not specified

Marine pollutant

Not specified

Other information

No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations

Not specified