Sulfamethoxazole
- CAS Number
- 723-46-6
- HSN Code
- 29355001
- Molecular Formula
- C10H11N3O3S
- Catalogue Number
- AL4395
- Purity
- 98% min
- Molecular Weight
- 253.28 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Sulfamethoxazole is an isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
Also known as Sulfamethoxazole, SMX.
- Catalogue No.
- AL4395
- CAS Number
- 723-46-6
- Molecular Formula
- C10H11N3O3S
- Molecular Weight
- 253.28 g/mol
- HSN Code
- 29355001
- Grade
- Extra Pure
- Product Form
- Substance
Melting point: 167 °C; Solubility: less than 1 mg/mL at 68 °F.
- Appearance
- Yellow-white powder
- Shelf Life
- 2 years
- Packaging
- Available in: 25 gm glass bottle, 100 gm glass bottle, 500 gm glass bottle
- Storage
- Commercially available sulfamethoxazole tablets and oral suspension should be protected from light and stored at a temperature less than 40 °C, preferably between 15-30 °C; freezing of the oral suspension should be avoided.
1.1 — Product identifier
- Chemical Name
- Sulfamethoxazole
- Catalogue No.
- AL4395
- Product form
- Substance
- CAS Number
- 723-46-6
- EC Number
- 211-963-3
- Grade
- Extra Pure
- EC Index Number
- 613-058-00-2
- Chemical Formula
- C10H11N3O3S
- HSN Code
- 29355001
- Synonyms
- Sulfamethoxazole, SMX
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Antibiotic, pharmaceutical reference standard
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Not classified as hazardous (majority of notifications to the ECHA C&L Inventory)
- Classification source
- ECHA C&L Inventory via PubChem CID 5329 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- None required
- Signal word
- None
- Hazard statements
- None
2.3 — Other hazards
- Other hazards
- None identified
3.1 — Substance
- Name
- Sulfamethoxazole
- CAS No.
- 723-46-6
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water.
- First-aid measures after eye contact
- First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- May cause allergic reactions, skin irritation, or gastrointestinal disturbances.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- May emit toxic fumes in a fire. Use water spray, foam, or dry chemical to extinguish.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and collect using appropriate protective equipment. Dispose of in accordance with local regulations.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use appropriate personal protective equipment. Sweep up and place in a suitable container for disposal.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Handle with gloves and avoid contact with skin and eyes. Use in a well-ventilated area.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Commercially available sulfamethoxazole tablets and oral suspension should be protected from light and stored at a temperature less than 40 °C, preferably between 15-30 °C; freezing of the oral suspension should be avoided.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if dust is generated.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White to pale yellow
- Odour
- Odorless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 167 °C
- Freezing point
- Not applicable
- Boiling point
- 360 °C
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.4 g/cm³
- Solubility
- less than 1 mg/mL at 68 °F
- Log Pow
- 0.89
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions, but may react with strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable in air.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents, strong acids, and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- When heated to decomposition it emits very toxic fumes of nitroxides and sulfoxides.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 Mouse oral 2650 mg/kg; LD50 Mouse ip 2300 mg/kg; LD50 Rat ip 2690 mg/kg
- Skin corrosion/irritation
- Not classified (based on available data)
- Serious eye damage/irritation
- Not classified (based on available data)
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not classified as dangerous goods.
- UN-No. (IMDG)
- Not classified as dangerous goods.
- UN-No. (IATA)
- Not classified as dangerous goods.
- UN-No. (ADN)
- Not classified as dangerous goods.
- UN-No. (RID)
- Not classified as dangerous goods.
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Not applicable
- Proper Shipping Name (IMDG)
- Not applicable
- Proper Shipping Name (IATA)
- Not applicable
- Proper Shipping Name (ADN)
- Not applicable
- Proper Shipping Name (RID)
- Not applicable
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Sulfamethoxazole is primarily used as a reference standard in pharmaceutical quality control, particularly in the development and testing of sulfonamide antibiotics like co-trimoxazole. It is also utilized in microbiological research to study bacterial resistance and the efficacy of antibiotic treatments. Additionally, sulfamethoxazole is employed in veterinary medicine for treating infections in animals. Its role in combination therapies enhances its effectiveness against a broader spectrum of bacterial pathogens.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1483E
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 253.28 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | 98% min | 98.5% |
| Melting Point | 165-170 °C | 168 °C |
| Moisture Content | <1% | 0.5% |
| Residue on Ignition | <0.1% | 0.05% |
| Related Substances | None detected | None detected |
The above product is expected to comply with Extra Pure grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| Extra Pure | 98% min | m.p. 167 °C | <1% | <0.1% | None detected | less than 1 mg/mL at 68 °F |
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