Cyanogen bromide
- CAS Number
- 506-68-3
- HSN Code
- 28530091
- Molecular Formula
- BrCN
- Catalogue Number
- AL1578
- Purity
- ≥ 99%
- Molecular Weight
- 105.93 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Cyanogen bromide is a colorless to white crystalline solid with a penetrating odor. It is slightly soluble in water.
Also known as Cyanobromide.
- Catalogue No.
- AL1578
- CAS Number
- 506-68-3
- Molecular Formula
- BrCN
- Molecular Weight
- 105.93 g/mol
- HSN Code
- 28530091
- Grade
- 99% For Synthesis
- Product Form
- Substance
Melting point: 52 °C; Boiling point: 61.5 °C; Density: 2.015 g/cu cm at 20 °C; Solubility: In water, soluble with hydrolysis.
- Appearance
- White hygroscopic needles
- Shelf Life
- -
- Packaging
- Available in: 100 gm glass bottle, 500 gm glass bottle
- Storage
- Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed.
1.1 — Product identifier
- Chemical Name
- Cyanogen bromide
- Catalogue No.
- AL1578
- Product form
- Substance
- CAS Number
- 506-68-3
- EC Number
- 208-051-2
- Grade
- 99% For Synthesis
- EC Index Number
- Not specified
- Chemical Formula
- BrCN
- HSN Code
- 28530091
- Synonyms
- Cyanobromide
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Reagent for protein cleavage and polysaccharide activation.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Acute Tox. 2; Skin Corr. 1B; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1
- Classification source
- ECHA C&L Inventory via PubChem CID 10476 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Corrosive, Acute Toxic, Environmental Hazard
- Signal word
- Danger
- Hazard statements
- H300+H310+H330: Fatal if swallowed, in contact with skin or if inhaled; H300: Fatal if swallowed; H310: Fatal in contact with skin; H314: Causes severe skin burns and eye damage; H318: Causes serious eye damage; H330: Fatal if inhaled; H400: Very toxic to aquatic life; H410: Very toxic to aquatic life with long lasting effects
- Precautionary statements
- P260, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P320, P321, P330, P361+P364, P363, P391, P403+P233, P405, P501
2.3 — Other hazards
- Other hazards
- Extremely toxic; releases cyanide upon hydrolysis.
3.1 — Substance
- Name
- Cyanogen bromide
- CAS No.
- 506-68-3
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention immediately.
- First-aid measures after skin contact
- Remove contaminated clothing. Wash skin with soap and water. Seek medical attention if irritation persists.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Seek medical attention immediately.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth and seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Toxic effects may include headache, dizziness, nausea, and respiratory distress.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- The vapour is heavier than air.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Wear appropriate protective equipment. Contain and neutralize spill.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Handle under a fume hood with appropriate PPE. Avoid contact with skin and eyes.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use a NIOSH-approved respirator if exposure limits are exceeded.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Penetrating
- Odour threshold
- Not specified
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- 52 °C
- Freezing point
- Not specified
- Boiling point
- 61.5 °C
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable under normal conditions
- Vapour pressure
- Vapor pressure = 115.6 mm Hg at 25 C extrapolated
- Relative vapour density at 20°C
- 3.62 (Air = 1)
- Density
- 2.015 g/cu cm at 20 °C
- Solubility
- In water, soluble with hydrolysis
- Log Pow
- Not specified
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Reacts violently with water, releasing toxic gases.
10.2 — Chemical stability
- Chemical stability
- Cyanogen bromide is moderately endothermic & shows evidence of instability.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Decomposes on heating and on contact with acids. This produces highly toxic and flammable hydrogen cyanide (see ICSC 0492) and corrosive hydrogen bromide (see ICSC 0282). Reacts with strong oxidants.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizers, strong acids, and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- If involved in a fire decomposes to produce toxic gases.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 (oral, rat) 10 mg/kg; highly toxic.
- Skin corrosion/irritation
- H314: Causes severe skin burns and eye damage
- Serious eye damage/irritation
- H318: Causes serious eye damage
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 1889
- UN-No. (IMDG)
- UN 1889
- UN-No. (IATA)
- UN 1889
- UN-No. (ADN)
- UN 1889
- UN-No. (RID)
- UN 1889
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Cyanogen bromide
- Proper Shipping Name (IMDG)
- Cyanogen bromide
- Proper Shipping Name (IATA)
- Cyanogen bromide
- Proper Shipping Name (ADN)
- Cyanogen bromide
- Proper Shipping Name (RID)
- Cyanogen bromide
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1 (8)
14.4 — Packing group
- Packing group (ADR)
- I
- Packing group (IMDG)
- I
- Packing group (IATA)
- I
- Packing group (ADN)
- I
- Packing group (RID)
- I
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used to cleave proteins at methionine residues (CNBr cleavage) and to activate agarose/Sepharose supports for affinity chromatography.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL00578
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 105.93 g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | White crystals | White crystals |
| Assay | (Min.) 99.0% | 99.14% |
| Melting point | 49 - 51°C | 50°C |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 99% For Synthesis | ≥ 99% | m.p. 52 °C; b.p. 61.5 °C | ≤ 0.5% | ≤ 0.1% | None detected | In water, soluble with hydrolysis |
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“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
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