Ethyl Chloroformate
- CAS Number
- 541-41-3
- HSN Code
- 29153990
- Molecular Formula
- C3H5ClO2
- Catalogue Number
- AL2065
- Purity
- ≥ 97%
- Molecular Weight
- 108.32 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Ethyl chloroformate appears as a colorless liquid with a pungent odor. Flash point 66 °F. Very toxic by inhalation.
Also known as Ethyl chloroformate, Ethyl chloroformate reagent.
- Catalogue No.
- AL2065
- CAS Number
- 541-41-3
- Molecular Formula
- C3H5ClO2
- Molecular Weight
- 108.32 g/mol
- HSN Code
- 29153990
- Grade
- 97% For Synthesis
- Product Form
- Substance
Melting point: -80.6 °C; Boiling point: 95 °C @ 760 MM HG; Flash point: 16 °C; Density: 1.1403 @ 20 °C/4 °C; Solubility: Solubility in water: reaction.
- Appearance
- Colourless liquid with pungent odour
- Shelf Life
- 12 months
- Packaging
- Available in: 500 ml glass bottle, 2.5 Lt glass bottle
- Storage
- Fireproof. Separated from strong oxidants, food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Dry. Well closed.
1.1 — Product identifier
- Chemical Name
- Ethyl Chloroformate
- Catalogue No.
- AL2065
- Product form
- Substance
- CAS Number
- 541-41-3
- EC Number
- 208-778-5
- Grade
- 97% For Synthesis
- EC Index Number
- 607-007-00-8
- Chemical Formula
- C3H5ClO2
- HSN Code
- 29153990
- Synonyms
- Ethyl chloroformate, Ethyl chloroformate reagent
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Reagent for organic synthesis, particularly in peptide coupling and ester synthesis.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Flam. Liq. 2; Acute Tox. 3; Skin Corr. 1B; Eye Dam. 1; Acute Tox. 2
- Classification source
- ECHA C&L Inventory via PubChem CID 10928 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Flammable, Corrosive, Acute Toxic
- Signal word
- Danger
- Hazard statements
- H225: Highly Flammable liquid and vapor; H301: Toxic if swallowed; H314: Causes severe skin burns and eye damage; H318: Causes serious eye damage; H330: Fatal if inhaled
2.3 — Other hazards
- Other hazards
- May cause respiratory irritation; may be harmful if inhaled.
3.1 — Substance
- Name
- Ethyl Chloroformate
- CAS No.
- 541-41-3
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Remove to fresh air; use artificial respiration if breathing has stopped; call a doctor; keep victim quiet and administer oxygen if needed.
- First-aid measures after skin contact
- Wash liberally with water for at least 15 min., then apply dilute solution of sodium bicarbonate or commercially prepared neutralizer.
- First-aid measures after eye contact
- Flush with water for at least 15 min.; see a doctor.
- First-aid measures after ingestion
- Do NOT induce vomiting; give large amount of water; get medical attention.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Coughing, shortness of breath, skin irritation, eye irritation.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Flammable liquid. Vapors are heavier than air & may travel to a source of ignition & flash back.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area. Ventilate. Use appropriate protective equipment. Contain spill.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Evacuate danger area! Consult an expert! Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood with appropriate PPE including gloves and goggles.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Fireproof. Separated from strong oxidants, food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Dry. Well closed.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use NIOSH-approved respirator if exposure limits are exceeded.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless to pale yellow
- Odour
- Sharp, like hydrochloric acid
- Odour threshold
- No data available
- pH value
- No data available
- Relative evaporation rate (butylacetate=1)
- No data available
- Melting point
- -80.6 °C
- Freezing point
- No data available
- Boiling point
- 95 °C @ 760 MM HG
- Flash point
- 16 °C
- Auto-ignition temperature
- 932 °F (500 °C)
- Decomposition temperature
- No data available
- Flammability (solid, gas)
- Flammable liquid
- Vapour pressure
- 22.4 mm Hg @ 25 °C
- Relative vapour density at 20°C
- 3.7 (AIR= 1)
- Density
- 1.1403 @ 20 °C/4 °C
- Solubility
- Solubility in water: reaction
- Log Pow
- No data available
- Viscosity, kinematic
- No data available
- Viscosity, dynamic
- No data available
- Explosive properties
- No data available
- Oxidising properties
- No data available
- Explosive limits
- No data available
10.1 — Reactivity
- Reactivity
- Reacts violently with strong bases and oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Decomposes on heating. This produces toxic and irritating fumes including hydrogen chloride and phosgene. Reacts with water and steam.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizers, strong bases, amines, alcohols.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Highly toxic; LD50 (oral, rat) 50 mg/kg.
- Skin corrosion/irritation
- H314: Causes severe skin burns and eye damage
- Serious eye damage/irritation
- H318: Causes serious eye damage
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 1182
- UN-No. (IMDG)
- UN 1182
- UN-No. (IATA)
- UN 1182
- UN-No. (ADN)
- UN 1182
- UN-No. (RID)
- UN 1182
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Ethyl Chloroformate
- Proper Shipping Name (IMDG)
- Ethyl Chloroformate
- Proper Shipping Name (IATA)
- Ethyl Chloroformate
- Proper Shipping Name (ADN)
- Ethyl Chloroformate
- Proper Shipping Name (RID)
- Ethyl Chloroformate
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1 (3, 8)
14.4 — Packing group
- Packing group (ADR)
- I
- Packing group (IMDG)
- I
- Packing group (IATA)
- I
- Packing group (ADN)
- I
- Packing group (RID)
- I
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as an activating reagent in mixed-anhydride peptide coupling reactions and carbamate/carbonate ester synthesis.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL00686
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 108.32 g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | A clear colorless liquid | A clear colorless liquid |
| Assay (GC) | Min 98% | 98.39% |
| D20°/4° | 1.138-1.140g | 1.139g |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 97% For Synthesis | ≥ 97% | m.p. -80.6 °C; b.p. 95 °C @ 760 MM HG | ≤ 0.5% | ≤ 0.1% | None detected | Solubility in water: reaction |
Related Products
View AllWhy buy from Alpha Chemika
What Our Scientific & Industrial Customers Say
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
FAQs
Common Questions About Laboratory Chemicals & Solutions
Find answers to common questions about laboratory chemicals, product selection, documentation, ordering, and technical support. Whether you are sourcing chemicals for research, testing, education, manufacturing, or industrial applications, these FAQs can help you make informed purchasing decisions.
Alpha Chemika offers a wide range of laboratory chemicals, reagents, solvents, and specialty products for research, testing, educational, pharmaceutical, and industrial applications.
Product selection depends on factors such as application, required purity, grade, specifications, and intended use. Our team can help you identify suitable products based on your technical requirements.
Yes. Relevant product information and technical documentation can be provided to help you evaluate products for quality, handling, compliance, and application requirements.
Yes. You can share your product list, required quantities, specifications, and delivery requirements with our team for a tailored quotation.
Yes. We support requirements from research laboratories, educational institutions, pharmaceutical companies, manufacturers, distributors, and other scientific and industrial organizations.
Connect with Us for Your Requirements
Have a specific product requirement or need help finding the right chemical for your application? Share your requirements with our team, and we will help you identify suitable products, specifications, quantities, and procurement options.
