Piperazine
- CAS Number
- 110-85-0
- HSN Code
- 29335990
- Molecular Formula
- C4H10N2
- Catalogue Number
- AL02472
- Purity
- ≥ 98%
- Molecular Weight
- 86.14 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Piperazine is an azacycloalkane that consists of a six-membered ring containing two nitrogen atoms at opposite positions. It has a role as an anthelminthic drug.
Also known as 1,4-Diazacyclohexane.
- Catalogue No.
- AL02472
- CAS Number
- 110-85-0
- Molecular Formula
- C4H10N2
- Molecular Weight
- 86.14 g/mol
- HSN Code
- 29335990
- Grade
- 98% For Synthesis
- Product Form
- Substance
Melting point: 106 °C; Boiling point: 146 °C; Flash point: 107 °C (Cleveland Open Cup); Density: 1.1 g/cu cm; Solubility: Mol wt 184.13. Minute crystals. Very slightly sol in water. pH of saturated aq soln 6.5.
- Appearance
- Plates or leaflets from ethanol
- Shelf Life
- 2 years
- Packaging
- Available in: 250 gm plastic bottle, 500 gm plastic bottle
- Storage
- Separated from strong acids, strong oxidants, acid anhydrides, metals and food and feedstuffs. Dry. Well closed.
1.1 — Product identifier
- Chemical Name
- Piperazine
- Catalogue No.
- AL02472
- Product form
- Substance
- CAS Number
- 110-85-0
- EC Number
- 203-808-3
- Grade
- 98% For Synthesis
- EC Index Number
- 612-002-00-4
- Chemical Formula
- C4H10N2
- HSN Code
- 29335990
- Synonyms
- 1,4-Diazacyclohexane
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Pharmaceutical synthesis
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Skin Corr. 1B; Skin Sens. 1B; Resp. Sens. 1B; Repr. 2
- Classification source
- ECHA C&L Inventory via PubChem CID 4837 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Corrosive, Health Hazard
- Signal word
- Danger
- Hazard statements
- H314: Causes severe skin burns and eye damage; H317: May cause an allergic skin reaction; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled; H361: Suspected of damaging fertility or the unborn child
2.3 — Other hazards
- Other hazards
- Hygroscopic; may cause skin and eye irritation.
3.1 — Substance
- Name
- Piperazine
- CAS No.
- 110-85-0
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water.
- First-aid measures after eye contact
- First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Irritation of the respiratory tract, skin, and eyes.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- May emit toxic fumes under fire conditions.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Wear appropriate protective equipment.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Ventilation. Sweep spilled substance into covered containers.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use gloves and safety goggles. Avoid contact with skin and eyes.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Separated from strong acids, strong oxidants, acid anhydrides, metals and food and feedstuffs. Dry. Well closed.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Typical amine odor
- Odour threshold
- Not specified
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- 106 °C
- Freezing point
- Not specified
- Boiling point
- 146 °C
- Flash point
- 107 °C (Cleveland Open Cup)
- Auto-ignition temperature
- 320 °C
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Vapor pressure = 2.6372X10+4 Pa @ 379.15 deg K
- Relative vapour density at 20°C
- 3.0 (air = 1)
- Density
- 1.1 g/cu cm
- Solubility
- Mol wt 184.13. Minute crystals. Very slightly sol in water. pH of saturated aq soln 6.5
- Log Pow
- -1.50
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not specified
10.1 — Reactivity
- Reactivity
- Stable under normal conditions, but may react with strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable at temperatures to 270 °C and in neutral or acid media.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Decomposes on burning. This produces toxic and corrosive gases including nitrogen oxides. The solution in water is a medium strong base.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizers, acids.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- When heated to decomposition it emits highly toxic fumes of nitrogen oxide.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 Rat oral 4,900 mg/kg; LD50 Rat oral 2,050 mg/kg; LD50 Mouse oral 6,200 mg/kg
- Skin corrosion/irritation
- H314: Causes severe skin burns and eye damage
- Serious eye damage/irritation
- Not classified (based on available data)
- Respiratory or skin sensitisation
- H317: May cause an allergic skin reaction; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- 2579
- UN-No. (IMDG)
- 2579
- UN-No. (IATA)
- 2579
- UN-No. (ADN)
- 2579
- UN-No. (RID)
- 2579
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Piperazine
- Proper Shipping Name (IMDG)
- Piperazine
- Proper Shipping Name (IATA)
- Piperazine
- Proper Shipping Name (ADN)
- Piperazine
- Proper Shipping Name (RID)
- Piperazine
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 8
14.4 — Packing group
- Packing group (ADR)
- III
- Packing group (IMDG)
- III
- Packing group (IATA)
- III
- Packing group (ADN)
- III
- Packing group (RID)
- III
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as the fundamental building block in fluoroquinolone antibiotics and numerous other piperazine-containing pharmaceutical syntheses.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL02472
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 86.14 g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | Off white flakes | Off white flakes |
| Assay | (Min.) 98% | 98.55% |
| Melting point | 108 - 111°C | 108.5°C |
| Water | <0.5% | 0.4% |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 98% For Synthesis | ≥ 98% | m.p. 106 °C; b.p. 146 °C | ≤ 0.5% | ≤ 0.1% | None detected | Mol wt 184.13. Minute crystals. Very slightly sol in water. pH of saturated aq soln 6.5 |
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