Propionic Anhydride
- CAS Number
- 123-62-6
- HSN Code
- 29155000
- Molecular Formula
- C6H10O3
- Catalogue Number
- AL3815
- Purity
- ≥ 98%
- Molecular Weight
- 130.14 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Propionic anhydride is a colorless liquid with a pungent odor. Flash point 165 °F. Density 8.4 lb /gal.
Also known as Propanoic anhydride.
- Catalogue No.
- AL3815
- CAS Number
- 123-62-6
- Molecular Formula
- C6H10O3
- Molecular Weight
- 130.14 g/mol
- HSN Code
- 29155000
- Grade
- 98%
- Product Form
- Substance
Melting point: -45 °C; Boiling point: 170 °C; Flash point: 165 °F (74 °C) (Open Cup); Density: 1.011 g/cu cm at 20 °C; Solubility: Decomposed by water; soluble in methanol, ethanol, ether and chloroform.
- Appearance
- Colorless liquid
- Shelf Life
- 12 months
- Packaging
- Available in: 500 ml glass bottle, 2.5 Lt glass bottle with tin cap
- Storage
- Dry. Ventilation along the floor. Separated from bases, oxidants and food and feedstuffs. Store only in original container.
1.1 — Product identifier
- Chemical Name
- Propionic Anhydride
- Catalogue No.
- AL3815
- Product form
- Substance
- CAS Number
- 123-62-6
- EC Number
- 204-638-2
- Grade
- 98%
- EC Index Number
- 607-007-00-8
- Chemical Formula
- C6H10O3
- HSN Code
- 29155000
- Synonyms
- Propanoic anhydride
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Acylating reagent in organic synthesis
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Skin Corr. 1B
- Classification source
- ECHA C&L Inventory via PubChem CID 31263 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Corrosive
- Signal word
- Danger
- Hazard statements
- H314: Causes severe skin burns and eye damage
2.3 — Other hazards
- Other hazards
- Corrosive to metals
3.1 — Substance
- Name
- Propionic Anhydride
- CAS No.
- 123-62-6
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move victim to fresh air; if breathing has stopped, give artificial respiration.
- First-aid measures after skin contact
- Immediately flush with plenty of water for at least 15 min.
- First-aid measures after eye contact
- Immediately flush with plenty of water for at least 15 min.; get medical attention.
- First-aid measures after ingestion
- Give large amount of water, do NOT induce vomiting.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Irritation of the skin, eyes, and respiratory tract; potential burns on contact.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- The vapour is heavier than air.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Contain spill and absorb with inert material.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Personal protection: chemical protection suit including self-contained breathing apparatus, face shield and protective gloves. Collect leaking liquid in sealable containers. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood with appropriate personal protective equipment (PPE).
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Dry. Ventilation along the floor. Separated from bases, oxidants and food and feedstuffs. Store only in original container.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless
- Odour
- Very rancid odor
- Odour threshold
- No data available
- pH value
- No data available
- Relative evaporation rate (butylacetate=1)
- No data available
- Melting point
- -45 °C
- Freezing point
- No data available
- Boiling point
- 170 °C
- Flash point
- 165 °F (74 °C) (Open Cup)
- Auto-ignition temperature
- 285 °C (545 °F)
- Decomposition temperature
- No data available
- Flammability (solid, gas)
- Flammable liquid
- Vapour pressure
- VP: 1 mm Hg at 20.6 °C
- Relative vapour density at 20°C
- 4.49 (Air = 1)
- Density
- 1.011 g/cu cm at 20 °C
- Solubility
- Decomposed by water; soluble in methanol, ethanol, ether and chloroform
- Log Pow
- No data available
- Viscosity, kinematic
- No data available
- Viscosity, dynamic
- No data available
- Explosive properties
- No data available
- Oxidising properties
- No data available
- Explosive limits
- No data available
10.1 — Reactivity
- Reactivity
- Reacts violently with water, releasing heat and forming propionic acid.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Decomposes on contact with water. This produces corrosive propionic acid (see ICSC 0806). Reacts violently with bases and oxidants.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Water, strong oxidizing agents, strong bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- When heated to decomposition it emits acrid smoke and irritating fumes.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 Rat oral 2360 mg/kg; LD50 Rabbit skin 10,000 mg/kg
- Skin corrosion/irritation
- H314: Causes severe skin burns and eye damage
- Serious eye damage/irritation
- Not classified (based on available data)
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 2496
- UN-No. (IMDG)
- UN 2496
- UN-No. (IATA)
- UN 2496
- UN-No. (ADN)
- UN 2496
- UN-No. (RID)
- UN 2496
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Propionic anhydride
- Proper Shipping Name (IMDG)
- Propionic anhydride
- Proper Shipping Name (IATA)
- Propionic anhydride
- Proper Shipping Name (ADN)
- Propionic anhydride
- Proper Shipping Name (RID)
- Propionic anhydride
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 8
14.4 — Packing group
- Packing group (ADR)
- III
- Packing group (IMDG)
- III
- Packing group (IATA)
- III
- Packing group (ADN)
- III
- Packing group (RID)
- III
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Propionic anhydride is widely used as a propionylating agent in organic synthesis, particularly in the pharmaceutical industry for the synthesis of propionyl derivatives of various compounds. It is also employed in the production of agrochemicals and in the preparation of esters and amides. Additionally, it finds applications in the synthesis of flavoring agents and fragrances, as well as in polymer chemistry for modifying polymer properties. Its versatility makes it a valuable reagent in both research and industrial applications.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1270A
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 130.14 g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | Clear colorless liquid | Clear colorless liquid |
| Assay (GC) | Min. 98.0% | 98.28% |
| Density (d 20°C/4°C) | 1.009 - 1.011 | 1.010 |
| Refractive index n20 o/D | About 1.4040 | 1.4040 |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 98% | ≥ 98% | m.p. -45 °C; b.p. 170 °C | ≤ 0.5% | ≤ 0.1% | None detected | Decomposed by water; soluble in methanol, ethanol, ether and chloroform |
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