Tetramethylammonium chloride
- CAS Number
- 75-57-0
- HSN Code
- 29239000
- Molecular Formula
- C4H12ClN
- Catalogue Number
- AL4501
- Purity
- ≥ 98%
- Molecular Weight
- 109.61 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
N,N,N-Trimethylmethanaminium chloride is an organic molecular entity.
Also known as TMAC, N,N,N-Trimethylmethanaminium chloride.
- Catalogue No.
- AL4501
- CAS Number
- 75-57-0
- Molecular Formula
- C4H12ClN
- Molecular Weight
- 109.61 g/mol
- HSN Code
- 29239000
- Grade
- For Synthesis
- Product Form
- Substance
Melting point: 420 °C (decomposes); Density: 1.1690 at 20 °C/4 °C; Solubility: Slightly soluble in ethanol; insoluble in ether, benzene, chloroform; very soluble in methanol.
- Appearance
- Bipyramidal from dilute alcohol
- Shelf Life
- 2 years
- Packaging
- Available in: 100 gm plastic bottle, 500 gm plastic bottle
- Storage
- Separated from oxidants. Dry. Well closed.
1.1 — Product identifier
- Chemical Name
- Tetramethylammonium chloride
- Catalogue No.
- AL4501
- Product form
- Substance
- CAS Number
- 75-57-0
- EC Number
- 200-880-8
- Grade
- For Synthesis
- EC Index Number
- 615-001-00-8
- Chemical Formula
- C4H12ClN
- HSN Code
- 29239000
- Synonyms
- TMAC, N,N,N-Trimethylmethanaminium chloride
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Used as a phase-transfer catalyst and in organic synthesis.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Acute Tox. 2; Acute Tox. 3; Skin Irrit. 2
- Classification source
- ECHA C&L Inventory via PubChem CID 6379 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Acute Toxic
- Signal word
- Danger
- Hazard statements
- H300: Fatal if swallowed; H311: Toxic in contact with skin; H315: Causes skin irritation
2.3 — Other hazards
- Other hazards
- May cause respiratory irritation; handle in a well-ventilated area.
3.1 — Substance
- Name
- Tetramethylammonium chloride
- CAS No.
- 75-57-0
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. Seek medical attention if irritation persists.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Symptoms of exposure may include irritation of the skin, eyes, and respiratory tract.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Toxic fumes may be released in a fire. Use appropriate fire-fighting measures.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and prevent entry into waterways. Wear appropriate protective equipment.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. Personal protection: P3 filter respirator for toxic particles.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid contact with skin and eyes. Use personal protective equipment as required.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Separated from oxidants. Dry. Well closed.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 420 °C (decomposes)
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.1690 at 20 °C/4 °C
- Solubility
- Slightly soluble in ethanol; insoluble in ether, benzene, chloroform; very soluble in methanol
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; avoid strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Decomposes above 300 °C . This produces ammonia, carbon monoxide, hydrogen chloride and nitrogen oxides. Reacts with oxidants.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents, strong acids.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- When heated to decomposition it emits very toxic fumes of nitrogen oxides, ammonia and hydrogen chloride.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 Mouse sc 40 mg/kg; LD50 Mouse ip 25 mg/kg
- Skin corrosion/irritation
- H315: Causes skin irritation
- Serious eye damage/irritation
- Not classified (based on available data)
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 2811
- UN-No. (IMDG)
- UN 2811
- UN-No. (IATA)
- UN 2811
- UN-No. (ADN)
- UN 2811
- UN-No. (RID)
- UN 2811
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (IMDG)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (IATA)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (ADN)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (RID)
- Toxic solid, organic, n.o.s.
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1
14.4 — Packing group
- Packing group (ADR)
- II
- Packing group (IMDG)
- II
- Packing group (IATA)
- II
- Packing group (ADN)
- II
- Packing group (RID)
- II
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Tetramethylammonium chloride is widely used in organic synthesis as a phase-transfer catalyst, which enhances the efficiency of reactions involving ionic compounds. It is particularly useful in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, TMAC serves as a reference compound in research studies involving quaternary ammonium salts, helping to elucidate reaction mechanisms and optimize synthetic pathways. Its ability to facilitate the transfer of reactants across phase boundaries makes it invaluable in both academic and industrial laboratories.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL2567A
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 109.61 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | 98 % min. | 98.23% |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| For Synthesis | ≥ 98% | m.p. 420 °C (decomposes) | ≤ 1% | ≤ 0.5% | None detected | Slightly soluble in ethanol; insoluble in ether, benzene, chloroform; very soluble in methanol |
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