Trifluoroacetic Acid
- CAS Number
- 76-05-1
- HSN Code
- 29159099
- Molecular Formula
- C2HF3O2
- Catalogue Number
- AL4660
- Purity
- ≥ 98%
- Molecular Weight
- 114.02 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Trifluoroacetic acid is a monocarboxylic acid that is the trifluoro derivative of acetic acid. It has a role as a reagent and a human xenobiotic metabolite.
Also known as TFA, Trifluoroacetic Acid.
- Catalogue No.
- AL4660
- CAS Number
- 76-05-1
- Molecular Formula
- C2HF3O2
- Molecular Weight
- 114.02 g/mol
- HSN Code
- 29159099
- Grade
- 98% Extra Pure
- Product Form
- Substance
Melting point: -15.4 °C; Boiling point: 72.4 °C; Density: 1.531 at 20 °C; Solubility: Miscible with ether, acetone, ethanol, benzene, carbon tetrachloride, hexane.
- Appearance
- Liquid
- Shelf Life
- -
- Packaging
- Available in: 100 ml glass bottle, 500 ml glass bottle, 1 Lt glass bottle, 2.5 Lt glass bottle
- Storage
- Separated from strong bases, metals, oxidants and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access.
1.1 — Product identifier
- Chemical Name
- Trifluoroacetic Acid
- Catalogue No.
- AL4660
- Product form
- Substance
- CAS Number
- 76-05-1
- EC Number
- 200-929-3
- Grade
- 98% Extra Pure
- EC Index Number
- 607-198-00-6
- Chemical Formula
- C2HF3O2
- HSN Code
- 29159099
- Synonyms
- TFA, Trifluoroacetic Acid
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Used in peptide synthesis and HPLC mobile phases.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.1 — Classification of the substance or mixture
- Classification according to Regulation (EC) No 1272/2008
- Skin Corr. 1A; Acute Tox. 4; Aquatic Chronic 3
- Classification source
- ECHA C&L Inventory via PubChem CID 6422 - hazard classes notified by at least 50% of companies; pictograms and signal word derived from those statements
2.2 — Label elements
- Hazard pictograms
- Corrosive, Irritant
- Signal word
- Danger
- Hazard statements
- H314: Causes severe skin burns and eye damage; H332: Harmful if inhaled; H412: Harmful to aquatic life with long lasting effects
2.3 — Other hazards
- Other hazards
- Corrosive to metals; may cause severe skin burns and eye damage.
3.1 — Substance
- Name
- Trifluoroacetic Acid
- CAS No.
- 76-05-1
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Remove to fresh air. If breathing is difficult, give oxygen. Seek medical attention immediately.
- First-aid measures after skin contact
- Remove contaminated clothing. Rinse skin with plenty of water for at least 15 minutes. Seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth. Seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Severe burns, respiratory distress, and irritation of the skin and eyes.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- The vapour is heavier than air.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area. Wear appropriate protective equipment. Contain spill and absorb with inert material.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable plastic containers. Absorb remaining liquid in sand or inert absorbent.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood with appropriate PPE including gloves and goggles. Avoid contact with skin and eyes.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Separated from strong bases, metals, oxidants and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless
- Odour
- Sharp biting odor
- Odour threshold
- Not specified
- pH value
- Not specified
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- -15.4 °C
- Freezing point
- Not specified
- Boiling point
- 72.4 °C
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Vapor pressure, kPa at 20 °C: 11
- Relative vapour density at 20°C
- Relative vapor density (air = 1): 3.9
- Density
- 1.531 at 20 °C
- Solubility
- Miscible with ether, acetone, ethanol, benzene, carbon tetrachloride, hexane.
- Log Pow
- -2.1
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Reacts violently with strong bases and oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- Decomposes on contact with hot surfaces or flames. This produces toxic fumes. The substance is a medium strong acid.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong bases, oxidizing agents, and metals.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- When heated to decomposition it emits toxic fumes of hydrogen fluorides.
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 Rat oral rat 200 mg/kg; LC50 Rat inhalation rat 10 g/cu m (duration unspecified); LC50 Mouse inhalation 13500 mg/cu m (Duration of exposure unspecified)
- Skin corrosion/irritation
- H314: Causes severe skin burns and eye damage
- Serious eye damage/irritation
- Not classified (based on available data)
- Respiratory or skin sensitisation
- Not classified (based on available data)
- Germ cell mutagenicity
- Not classified (based on available data)
- Carcinogenicity
- Not classified (based on available data)
- Specific target organ toxicity (single exposure)
- Not classified (based on available data)
- Specific target organ toxicity (repeated exposure)
- Not classified (based on available data)
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 2699
- UN-No. (IMDG)
- UN 2699
- UN-No. (IATA)
- UN 2699
- UN-No. (ADN)
- UN 2699
- UN-No. (RID)
- UN 2699
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Trifluoroacetic Acid
- Proper Shipping Name (IMDG)
- Trifluoroacetic Acid
- Proper Shipping Name (IATA)
- Trifluoroacetic Acid
- Proper Shipping Name (ADN)
- Trifluoroacetic Acid
- Proper Shipping Name (RID)
- Trifluoroacetic Acid
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 8
14.4 — Packing group
- Packing group (ADR)
- I
- Packing group (IMDG)
- I
- Packing group (IATA)
- I
- Packing group (ADN)
- I
- Packing group (RID)
- I
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Strong nonoxidizing acid, laboratory reagent, solvent, catalyst.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL02580
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 114.02 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 98% | 99.5% |
| Density | 1.489 g/mL | 1.490 g/mL |
| Boiling Point | 72 °C | 72.5 °C |
| Melting Point | -15 °C | -14.5 °C |
| Moisture Content | ≤ 0.5% | 0.3% |
| Residue on Ignition | ≤ 0.1% | 0.05% |
| Related Substances | None detected | None detected |
The above product is expected to comply with 98% Extra Pure grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 98% Extra Pure | ≥ 98% | m.p. -15.4 °C; b.p. 72.4 °C | ≤ 0.5% | ≤ 0.1% | None detected | Miscible with ether, acetone, ethanol, benzene, carbon tetrachloride, hexane. |
Related Products
View AllWhy buy from Alpha Chemika
What Our Scientific & Industrial Customers Say
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
FAQs
Common Questions About Laboratory Chemicals & Solutions
Find answers to common questions about laboratory chemicals, product selection, documentation, ordering, and technical support. Whether you are sourcing chemicals for research, testing, education, manufacturing, or industrial applications, these FAQs can help you make informed purchasing decisions.
Alpha Chemika offers a wide range of laboratory chemicals, reagents, solvents, and specialty products for research, testing, educational, pharmaceutical, and industrial applications.
Product selection depends on factors such as application, required purity, grade, specifications, and intended use. Our team can help you identify suitable products based on your technical requirements.
Yes. Relevant product information and technical documentation can be provided to help you evaluate products for quality, handling, compliance, and application requirements.
Yes. You can share your product list, required quantities, specifications, and delivery requirements with our team for a tailored quotation.
Yes. We support requirements from research laboratories, educational institutions, pharmaceutical companies, manufacturers, distributors, and other scientific and industrial organizations.
Connect with Us for Your Requirements
Have a specific product requirement or need help finding the right chemical for your application? Share your requirements with our team, and we will help you identify suitable products, specifications, quantities, and procurement options.
